Anti-fatigue ionic gels for long-term multimodal respiratory abnormality monitoring  

作　　者：Xiang-Jun Zha Jian-Bo Li Guo-Peng Liang Jun-Hong Pu Zhong-Wei Zhang Bo Wang Ji-Gang Huang Jin Jia Xin Zhao Kai-Qi Pan Mei-Ling Dong Kai Ke Yan Kang Wei Yang 

机构地区：[1]College of Polymer Science and Engineering,Sichuan University,State Key Laboratory of Polymer Materials Engineering,Chengdu 610065,Sichuan,China [2]Department of Critical Care Medicine,West China Hospital,Sichuan University,37 Guo Xue Xiang St,Chengdu 610041,Sichuan,China [3]Laboratory of Liver Transplantation,Frontiers Science Center for Disease-Related Molecular Network,West China Hospital of Sichuan University,Chengdu 610041,Sichuan,China [4]Centre for Advanced Macromolecular Design and Australian Centre for NanoMedicine,School of Chemical Engineering,UNSW Sydney,NSW 2052,Australia [5]School of Mechanical Engineering,Sichuan University,Chengdu 610065,Sichuan,China

出　　处：《Journal of Materials Science & Technology》2023年第20期99-108,共10页材料科学技术（英文版）

基　　金：supported by the National Natural Science Foundation of China(NNSFC grant No.52125301);the Sichuan Province Science and Technology Department Project(grant No.2021YJ0448);the Post Doctoral Research Fund,West China Hospital,Sichuan University(grant No.2020HXBH181);We thank Shanghai Synchrotron Radiation Facility(SSRF)BL16B1 for providing technological support for SAXS and WAXD characterization。

摘　　要：Wearable electronics integrated with stretchable sensors are considered a promising and non-invasive strategy to monitor respiratory status for health assessment.However,long-term and stable monitoring of respiratory abnormality is still a grand challenge.Here,we report a facile one-step thermal stretching strategy to fabricate an anti-fatigue ionic gel(AIG)sensor with high fatigue threshold(0=1130 J m^(–2)),high stability(>20,000 cycles),high linear sensitivity,and recyclability.A multimodal wearable respiratory monitoring system(WRMS)developed with AIG sensors can continuously measure respiratory abnormality(single-sensor mode)and compliance(multi-sensor mode)by monitoring the movement of the ribcage and abdomen in a long-term manner.For single-sensor mode,the respiratory frequency(Fr),respiratory energy(Er),and inspire/expire time(I/E ratio)can be extracted to evaluate the respiratory status during sitting,sporting,and sleeping.Further,the multi-sensors mode is developed to evaluate patientventilator asynchrony through validated clinical criteria by monitoring the incongruous movement of the chest and abdomen,which shows great potential for both daily home care and clinical applications.

关 键 词：Anti-fatigue ionic gels Wearable electronics Multimodal respiratory monitoring 

分 类 号：R318.6[医药卫生—生物医学工程] TH789[医药卫生—基础医学]