正交实验优化重楼皂苷Ⅰ的微波提取工艺  

Optimization in Microwave Extraction Process of PolyphyllinⅠby Orthogonal Experiment

作　　者：张雪娇[1] 王月 范涛[1] 成昭[1] ZHANG Xuejiao;WANG Yue;FAN Tao;CHENG Zhao(College of Pharmacy,Xi′an Medical University,Xi′an 710021,China)

机构地区：[1]西安医学院药学院,陕西西安710021

出　　处：《化学与生物工程》2023年第8期26-30,共5页Chemistry & Bioengineering

基　　金：陕西省科技厅项目(2021JM-502);西安医学院博士启动项目(2020DOC32);国家级大学生创新创业训练计划项目(202211840014)。

摘　　要：在单因素实验的基础上,通过正交实验优化重楼皂苷Ⅰ的微波提取工艺。确定最佳提取工艺为:乙醇体积分数45%、微波功率300 W、微波温度80℃、微波时间35 min、料液比1∶15(g∶mL),在此条件下,重楼皂苷Ⅰ提取率达到5.47%。该方法操作简单、省时、高效,可用于重楼皂苷Ⅰ的提取。We optimized the microwave extraction process of polyphyllinⅠby orthogonal experiments on the basis of single-factor experiments.The optimum extraction conditions are determined as follows:the ethanol volume fraction of 45%,the microwave power of 300 W,the microwave temperature of 80℃,the microwave time of 35 min,and the solid-liquid ratio of 1∶15(g∶mL).Under above conditions,the extraction rate of polyphyllinⅠcan reach 5.47%.This method is simple,time-saving,and efficient,which can be used for the extraction of polyphyllinⅠ.

关 键 词：重楼皂苷Ⅰ 微波提取 正交实验 

分 类 号：TQ461[化学工程—制药化工] R284[医药卫生—中药学]