中药内服外治对盆腔炎性疾病伴不孕患者卵巢储备功能及性激素水平的影响  

The Effect of Oral Administration and External Treatment of Traditional Chinese Medicine on Ovarian Reserve Function and Sex Hormone Levels in Patients with Pelvic Inflammatory Disease and Infertility

作　　者：黄鹏 潘丽贞 王英 HUANG Li;PAN Lizhen;WANG Ying(Department of Obstetrics and Gynecology,Nanping People's Hospital,Nanping353000,Fujian Province,China)

机构地区：[1]南平市人民医院妇产科,福建南平353000

出　　处：《中国实用乡村医生杂志》2023年第4期29-32,36,共5页Chinese Practical Journal of Rural Doctor

摘　　要：目的 探讨中药内服外治对盆腔炎性疾病(pelvic inflammatory disease,PID)伴不孕患者卵巢储备功能及性激素水平的影响。方法 收集2020年1月—2021年1月南平市人民医院收治的湿热瘀结型PID伴不孕患者70例作为研究对象,并按随机数字表法分为对照组和观察组各35例。对照组接受西药和中药内服治疗;观察组接受常规西药、中药内服和中药外治(中药保留灌肠、中药熏蒸、穴位注射)。比较两组中医证候评分、激素水平和卵巢储备功能改善情况。结果 治疗后,观察组舌脉、妇科、腹部及其他症候评分均低于对照组,差异有统计学意义(P<0.05);观察组的卵泡刺激素、黄体生成素水平低于对照组,而抗缪勒氏管激素水平高于对照组,差异有统计学意义(P<0.05);观察组卵巢直径、卵巢体积、双侧卵巢基础窦卵泡数目大于对照组,差异有统计学意义(P<0.05)。结论 中药内服外治可有效改善PID伴不孕患者的中医证候,调节性激素水平,提高卵巢储备功能。Objective To explore the effects of oral and external administration of traditional Chinese medicine on ovarian reserve function and sex hormone levels in patients with pelvic inflammatory disease(PID)and infertility.Methods A total of 70 patients with dampness heat stasis type PID and infertility admitted to Nanping People's Hospital from January 2020 to January 2021 were collected as research subjects,and were randomly divided into a control group and an observation group with 35 cases each.The control group received Western medicine and traditional Chinese medicine orally.The observation group received conventional Western medicine,oral administration of traditional Chinese medicine,and external treatment of traditional Chinese medicine(retention enema,fumigation,and acupoint injection of traditional Chinese medicine).The improvement of traditional Chinese medicine syndrome scores,hormone levels,and ovarian reserve function were compared between two groups.Results Afer treatment,the scores of tongue and pulse,gynecology,abdomen,and other symptoms in the observation group were significantly lower than those in the control group(P<0.05).The levels of follicle stimulating hormone and luteinizing hormone in the observation group were significantly lower than those in the control group,while the levels of anti-Mullerian hormone were significantly higher than those in the control group(P<0.05).The observation group had a significant difference in ovarian diameter,ovarian volume,and the number of basal ovarian follicles on both sides compared to the control group(P<0.05).Conclusion Oral administration and external treatment of traditional Chinese medicine can effectively improve the traditional Chinese medicine syndrome of PID patients with infertility,regulate sexual hormone levels,and enhance ovarian reserve function.

关 键 词：盆腔炎性疾病 不孕症 中西医结合 卵巢储备功能 性激素 

分 类 号：R271[医药卫生—中医妇科学]