Lp-PLA2水平在动脉粥样硬化中的意义及临床研究进展  

Significance and clinical research progress of Lp-PLA2 level in atherosclerosis

作　　者：敖希瑾(综述) 宋耀鸿(审校)[2] AO Xijin;SONG Yaohong(Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China;Department of Cardiovascular Medicine,Nanjing Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu 210022,China)

机构地区：[1]南京中医药大学,江苏南京210023 [2]南京市中医院心血管内科,江苏南京210022

出　　处：《现代医药卫生》2023年第15期2615-2618,共4页Journal of Modern Medicine & Health

基　　金：南京中医药大学自然科学基金项目(XZR2020047)。

摘　　要：动脉粥样硬化(AS)是临床常见的血管炎症性疾病,是心脑血管病、血栓栓塞性疾病等的重要病理基础。脂蛋白相关磷脂酶A2(Lp-PLA2)作为一种血管炎症因子,血浆Lp-PLA2水平可反映AS斑块的稳定性和炎症的严重程度及疾病的预后等。该文对Lp-PLA2水平在AS中的意义及临床研究进展进行了综述。Atherosclerosis(AS)is a common vascular inflammatory disease in clinic,which is an important pathological basis for cardiovascular and cerebrovascular diseases,thromboembolic diseases and other diseases.Lipoprotein-associated phospholipase A2(Lp-PLA2)is a kind of vascular inflammatory factor.The level of plasma Lp-PLA2 can reflect the stability of AS plaque,the severity of inflammation,and the prognosis of the disease.This article reviewed the significance of Lp-PLA2 level in AS and its clinical research progress.

关 键 词：动脉粥样硬化 脂蛋白相关磷脂酶A2 血管炎症 综述 

分 类 号：R543.5[医药卫生—心血管疾病]