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作 者:闫怡安 邓欣然 姜玥 李小号[1] 谢元华[1] 刘坤[1] YAN Yian;DENG Xinran;JIANG Yue;LI Xiaohao;XIE Yuanhua;LIU Kun(School of Mechanical Engineering and Automation,Northeastern University,Shenyang 110819,China;China Kunlun Contracting&Engineering Corporation,Beijing 100037,China)
机构地区:[1]东北大学机械工程与自动化学院,沈阳110819 [2]中国昆仑工程有限公司,北京100037
出 处:《真空科学与技术学报》2023年第7期569-576,共8页Chinese Journal of Vacuum Science and Technology
基 金:辽宁省应用基础研究计划项目(2022JH2/101300215);沈阳市自然科学基金(22-315-6-01)。
摘 要:微混合器是微芯片集成系统中重要的组成部分,广泛应用于生物分析,化学合成等领域。为了提高被动式微混合器在低雷诺数层流条件下的混合效率,本文设计了一种人字脊蛇形通道微混合器并对其混合结构和流体参数展开分析研究。在人字脊高度和角度对流体混合作用研究的基础上,取人字脊角度θ=45°,d/H为1/2时,分析流量大小对混合效果的影响。同时,选用PBS溶液和台盼蓝染色液进行实验测试,综合评估微混合器混合性能。结果表明:在一定结构参数取值范围内,人字脊高度与通道高度之比越大,流体混合越充分,最佳人字脊角度在40°~50°之间;流体流动速度越小,混合质量越高。模拟和实验平均误差不超过10%,具有良好的一致性。本研究为被动式微混合器混合效率的提升提供参考。Micromixer is an important part of microchip integrated system,widely used in biological analysis,chemical synthesis and other fields.In order to improve the mixing efficiency of passive micromixers under low Reynolds number laminar flow conditions,a serpentine channel micromixer with herringbone ridges was designed in this paper,and its mixing structure and fluid parameters were analyzed.Based on the study on the effect of herringbone ridges height and angle on fluid mixing,the influence of flow rate on mixing effect was analyzed when the herringbone ridges angleθ=45°and d/H was 1/2.At the same time,PBS solution and Trypan blue dyeing solution were selected for experimental tests to comprehensively evaluate the mixing performance of the micromixer.The results show that,in a certain range of structural parameters,the greater the ratio of herringbone height to channel height,the more sufficient the fluid mixing,and the optimal herringbone angle is between 40°and 50°.The lower the flow velocity,the higher the mixing quality.The average error of simulation and experiment is less than 10%.This study provides a reference for improving the mixing efficiency of passive micromixers.
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