麻黄粉贴敷肺俞穴对特定穴位激光散斑血流成像的影响  

Effect of Herbal Patching of Mahuang(Herba Ephedrae)Powder at Feishu(BL13)on Laser Speckle Blood Flow Imaging of Specific Acupoints

作　　者：马杭琨 王淑友[2] 宋晓晶[2] 郭曼萍 王一名 栗蕊 高蕊[1] MA Hangkun;WANG Shuyou;SONG Xiaojing;GUO Manping;WANG Yiming;LI Rui;GAO Rui(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091;Institute of Acupuncture and Moxibus-tion,China Academy of Chinese Medical Sciences;Postdoctoral Workstation of Yabao Pharmaceutical Group Co.,Ltd.;The First Affiliated Hospital of Henan University of Chinese Medicine)

机构地区：[1]中国中医科学院西苑医院,北京市100091 [2]中国中医科学院针灸研究所 [3]亚宝药业集团股份有限公司博士后工作站 [4]河南中医药大学第一附属医院

出　　处：《中医杂志》2023年第15期1565-1570,共6页Journal of Traditional Chinese Medicine

基　　金：中国中医科学院科技创新工程(CI2021A04701)。

摘　　要：目的 探索应用麻黄粉贴敷肺俞穴对背部及气管-支气管解剖部位所对应的体表穴位的血流灌注的影响。方法 纳入10位健康受试者,男、女各5人,采用自身前后对照,应用麻黄粉贴敷双侧肺俞穴180 min。贴敷前和贴敷180 min后应用可视化激光散斑血流成像技术监测受试者双侧肺俞、双侧魄户、身柱、廉泉、天突、膻中、双侧神封和双侧膺窗的血流灌注成像变化,贴敷60 min和120 min监测除肺俞穴外的所有穴位。比较同一穴位随贴敷时间变化血流灌注量的变化情况,以及同一时间不同穴位间血流灌注量。结果 受试者贴敷前后体温、心率、血压和食指末梢血氧饱和度变化均无统计学意义(P>0.05)。激光散斑血流成像图直观显示:贴敷前气管-支气管解剖结构所对应的体表穴位较之背部腧穴血流灌注量更大。贴敷180 min后,背部腧穴和颈部腧穴激光散斑血流灌注成像图变化不明显,胸部腧穴血流灌注量较贴敷前减少。右侧肺俞穴贴敷180 min后血流灌注量较贴敷前上升84.35 PU (P<0.05),其余穴位贴敷前后血流灌注量差异无统计学意义(P>0.05)。贴敷前,膻中穴、神封穴(右)、膺窗穴(右)血流灌注量显著低于天突穴(P<0.05或P<0.01);贴敷180 min后,膻中穴、神封穴(右)、膺窗穴(右)及神封穴(左)、膺窗穴(左)血流灌注量均低于天突穴(P<0.05或P<0.01)。穴位血流灌注随贴敷时间变化分析显示,天突穴的血流灌注量均值波动在800~900 PU,廉泉、神封(左)和膺窗(左)血流灌注量均值波动在500~600 PU,差异无统计学意义(P>0.05)。结论 应用麻黄粉贴敷肺俞穴对贴敷部位局部以及气管-支气管解剖结构所对应的体表穴位血流灌注无明显影响。Objective To explore the effect of Mahuang(Herba Ephedrae)powder stick at Feishu(BL13)on the blood perfusion of body surface acupoints corresponding to the anatomical site of back and trachea-bronchus.Methods Ten healthy subjects were included,involving 5 males and 5 females.A single group of self-control was used to apply Mahuang powder to bilateral Feishu(BL13)for 180 minutes.The blood perfusion imaging changes of bilateral Feishu(BL13),bilateral Pohu(BL42),Shenzhu(GV12),Lianquan(CV23),Tiantu(CV22),Danzhong(CV17),bilateral Shenfeng(KI23)and bilateral Yingchuang(ST16)were monitored by visual laser speckle blood flow imaging before and 180 minutes after herbal patching,and all those except for Feishu(BL13)were measured 60 and 120 minutes after patching as well.The changes of blood perfusion at the same acupoint with the time of herbal patching,and the differences of blood perfusion between different acupoints at the same time were analyzed.Results There were no statistically significant changes in body temperature,heart rate,blood pressure,and oxygen saturation at the tip of the index finger in healthy subjects before and after herbal patching(P>0.05).Laser speckle blood flow imaging showed that the blood perfusion of the surface acupoints corresponding to the tracheal-bronchial anatomical site was larger than that of the dorsal acupoints before and after herbal patching.After 180 minutes,the laser speckle blood perfusion images of back and neck acupoints did not change significantly,while the blood perfusion of chest acupoints was reduced compared with that before herbal patching.Except for the blood perfusion of the right Feishu(BL13)increasing by 84.4 PU after 180 minutes(P<0.05),there was no significant difference in blood perfusion of other acupoints(P>0.05).Before herbal patching,blood perfusion of Danzhong(CV17),right Shenfeng(KI23),right Yingchuang(ST16)was significantly lower that of Tiantu(CV22)(P<0.05 or P<0.01);after 180 minutes,the blood perfusion of Danzhong(CV17),right Shenfeng(KI23),right Yingchua

关 键 词：穴位贴敷 麻黄 肺俞穴 血流灌注 激光散斑血流成像 

分 类 号：R246.1[医药卫生—针灸推拿学]