干眼症患者药物治疗管理模式的建立和评价  

Establishment and evaluation of drug therapy management system for patients with dry eye

作　　者：陆海[1] 王兴 闫瑾[1] 陈陆霞[2] 马一平 LU Hai;WANG Xing;YAN Jin;CHEN Luxia;MA Yiping(Department of Pharmacy,Tianjin Eye Hospital,Tianjin 300120,China;Department of Ocular Surface Keratology,Tianjin Eye Hospital,Tianjin 300120,China)

机构地区：[1]天津市眼科医院,药剂科,天津300120 [2]天津市眼科医院,眼表角膜病科,天津300120

出　　处：《中国医院药学杂志》2023年第14期1624-1628,共5页Chinese Journal of Hospital Pharmacy

基　　金：白求恩医学科学研究项目(编号:BJ-GY20211019J)。

摘　　要：目的:初步建立干眼症患者的药物治疗管理(medication therapeutical management,MTM)模式,并探讨其干预效果。方法:选取2021年1—12月就诊于天津市眼科医院门诊的140例干眼症患者,将其随机分为干预组和对照组,干预组接受至少3次完整的MTM服务,对照组接受普通的门诊药学咨询。随访3个月后,统计2组患者在经济、临床、人文及解决药治疗物相关问题(medication,related problems,MRPs)的改善情况,评价MTM实施的效果。结果:与对照组比较,经过3个月的MTM服务后,干预组在经济结果、临床结局、人文评价、解决MRPs方面差异具有统计学意义(P<0.05)。结论:由药师主导的MTM模式,能够显著降低药品成本、改善临床指标、提升生活质量,患者对MTM服务满意度高,值得在干眼症临床治疗中推广。OBJECTIVE To establish a medication therapeutical management(MTM)system for patients with dry eye,and to explore the effect of this intervention.METHODS A total of 140 patients with dry eye disease admitted to the outpatient department of Tianjin Eye Hospital from January to December 2021 were selected and randomly divided into intervention group and control group.The intervention group received complete MTM service for at least 3 times,and the control group received general outpatient pharmaceutical consultation.After 3 months of follow-up,the improvement of medication,clinical,humanistic and MRPs in the 2 groups was analyzed,and the effect of MTM implementation was evaluated.A total of 140 patients with dry eye disease admitted to the outpatient department of Tianjin Eye Hospital from January to December 2021 were selected and randomly divided into intervention group and control group.The intervention group received complete MTM service for at least 3 times,and the control group received general outpatient pharmaceutical consultation.After 3 months of follow-up,the improvement of medication,clinical,humanistic and MRPs in the 2 groups was analyzed,and the effect of MTM implementation was evaluated.RESULTS Compared with the control group,after 3 months of MTM service,the intervention group had significant differences in economic results,clinical outcomes,humanistic evaluation and MRPs resolution,with statistical significance(P<0.05).CONCLUSION A pharmacist-led MTM model can significantly reduce drug costs,improve clinical indicators,enhance quality of life,and result in high patient satisfaction with MTM services.Therefore,it is worth promoting in clinical practice for dry eye patients.

关 键 词：药物治疗管理 干眼症 药物相关问题 效果评价 

分 类 号：R988.1[医药卫生—药品]