四黄水蜜外敷疗法治疗血液透析患者动静脉内瘘穿刺肿痛的疗效观察  

The efficacy of external application therapy by Sihuang Shuimi Powder on puncture and swelling pain in patients with arteriovenous fistula

作　　者：曾志力[1] 林克兰 李庆 肖俊南[1] 肖雅倩 ZENG Zhili;LIN Kelan;LI Qing;XIAO Junnan;XIAO Yaqian(Department of Blood Purification,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510260,China;Guangzhou Medical University,Guangzhou,Guangdong 510260,China;Nanhai People’s Hospital,Foshan,Guangdong 528000,China)

机构地区：[1]广州医科大学附属第二医院血液净化中心,广东广州510260 [2]广州医科大学,广东广州510260 [3]南海区人民医院,广东佛山528000

出　　处：《医药前沿》2023年第15期34-37,共4页Journal of Frontiers of Medicine

基　　金：广东省中医药局科研项目(20222124);广州市卫生健康科技项目(20222A011016);广州医科大学附属第二医院护理科研基金项目(A202010)。

摘　　要：目的:观察四黄水蜜外敷疗法治疗维持性血液透析患者动静脉内瘘穿刺肿痛的疗效。方法:选取2020年8月—2023年3月广州医科大学附属第二医院血透中心收治的动静脉内瘘穿刺肿痛的101例血透患者,应用随机数字表法将其分为药物1组(34例)、药物2组(33例)、安慰剂组(34例)。药物1组采用黄水蜜外敷,药物2组采用喜疗妥外涂,安慰剂组采用安慰剂制剂。分别在治疗前、治疗第7、14、28天评价患者的硬结大小、疼痛评分。结果:三组患者间的硬结大小变化在治疗后的第7、14、28天进行比较,差异均有统计学意义(P<0.01)。药物1组与药物2组的硬结伴随治疗时间延长,明显变小;且药物1组的效果明显优于药物2组和安慰剂组。三组间患者的疼痛评分在治疗后的第7、14天的比较,差异均有统计学意义(P<0.01),在治疗后的第28天数字评分量表(NRS)差异无统计学意义(P=0.296)。结论:四黄水蜜外敷与喜疗妥外涂对动静脉内瘘穿刺肿痛的患者的硬结消散及减缓疼痛均有效。Objective To investigate the efficacy of external application therapy by Sihuang Shuimi Powder on puncture and swelling pain in patients with arteriovenous fistula.Methods From August 2020 to March 2023,101 patients with arteriovenous fistula puncture and swelling pain in the hemodialysis center of our hospital were selected.The patients were divided into three groups,with 34 cases in the drug group 1,33 cases in the drug group 2,and 34 cases in the placebo group.Sihuang Shuimi Powder was applied externally in the drug group 1,Mucopolysaccharide Polysulfate Cream external application was used in the drug group 2,and placebo preparation was used in the placebo group.The size of induration and pain score were evaluated before the intervention and on the 7th,14th and 28th day of the intervention respectively,and to employ variance analysis.Results There were significant differences among the three groups in the changes of induration size on the 7th,14th and 28th days after treatment(P<0.01).In addition,the induration in the drug group 1 and the drug group 2 was significantly reduced with the time.The effect of drug group 1 was significantly better than that of drug group 2 and placebo group.The differences of pain scores(NRS)among the three groups on the 7th and 14th day after treatment were statistically significant(P<0.01),and there was no significant difference in NRS on the 28th day after treatment(P=0.296).Conclusion Sihuang Shuimi Powder and Mucopolysaccharide Polysulfate Cream were effective in removing the induration and relieving the pain.

关 键 词：四黄水蜜 外敷 动静脉内瘘 

分 类 号：R543.6[医药卫生—心血管疾病]