高血压肾病的研究进展  

Research progress of hypertensive nephropathy

作　　者：李永光 裴德根 刘睿涵 谢宇楠 林青扬 陈文佳[1] LI Yong-guang;PEI De-gen;LIU Rui-han;XIE Yu-nan;LIN Qing-yang;CHEN Wen-jia(Department of Cardiology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院心血管内科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2023年第4期383-387,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：国家自然科学基金(81800419)。

摘　　要：高血压肾病发病机制复杂,包括血管、肾小球、肾小管间质损伤等,并受遗传、环境等因素影响,因此探究其发病机制对于高血压肾病的诊断、预防及治疗意义重大。在治疗方面,高血压肾病出现了新兴的诊疗方法,并达到了一定的效果。但在降压靶目标的确定上仍存在争议。因此,现就高血压肾病的定义、损伤机制及治疗研究进展做一综述。Hypertensive nephropathy(HTN) possesses complex pathogenesis,including vascular,glomerular and tubulointerstitial injury etc,which is affected by genetic,environmental and other factors.Therefore,it is of great significance to explore its pathogenesis for the diagnosis,prevention and treatment of HTN.In terms of treatment,a new method of diagnosis and treatment of HTN has emerged,and achieved certain results.However,there is still controversy on the determination of pressure lowering target.Therefore,the present article reviews research progress of the definition,injury mechanism and treatment of HTN.

关 键 词：高血压 肾病 治疗 

分 类 号：R544.1[医药卫生—心血管疾病]