RBP4与代谢综合征的研究进展  

Research progress of RBP4 and metabolic syndrome

作　　者：宫博 姜晓艳[1] GONG Bo;JIANG Xiao-yan(Department of Endocrinology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院内分泌科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2023年第4期418-422,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：视黄醇结合蛋白4(RBP4)是新发现的脂肪因子,其通过基因单核苷酸多态性、干扰信号通路、诱导免疫炎症、损伤血管内皮等多种机制参与代谢综合征(MS)相关病理改变的发生与发展。深入研究RBP4与MS相关性及发生机制可为心血管疾病的预防、诊断及治疗提供新思路。Retinol binding protein 4(RBP4) is a newly discovered adipokine,which is involved in the occurrence and development of metabolic syndrome(MS)-related pathological changes through multiple mechanisms such as gene single nucleotide polymorphisms,interference in signaling pathways,induction of immune inflammation and injury of vascular endothelium.In-depth study on the correlation between RBP4 and MS and mechanism can provide new thinking for the prevention,diagnosis and treatment of cardiovascular diseases.

关 键 词：代谢综合征X 视黄醇结合蛋白类 心血管疾病 

分 类 号：R589[医药卫生—内分泌]