快速性心律失常的中医研究进展  

Advances in Treatment of Tachyarrhythmia with Traditional Chinese Medicine

作　　者：邱月清 王振涛[1,2] 王冰 郭宗耀[1,2] 边汝涛 孙乾 李习婉 刘庆阳 QIU Yueqing;WANG Zhentao;WANG Bing;GUO Zongyao;BIAN Rutao;SUN Qian;LI Xiwan;LIU Qingyang(Second Clinical Medicine College,Henan University of Chinese Medicine,Zhengzhou 450011,China;Henan Provincial Hospital of Chinese Medicine/The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450053,China;Zhengzhou Traditional Chinese Medicine Hospital,Zhengzhou 450006,China;The First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453199,China)

机构地区：[1]河南中医药大学第二临床医学院,郑州450011 [2]河南省中医院/河南中医药大学第二附属医院,郑州450053 [3]郑州市中医院,郑州450006 [4]新乡医学院第一附属医院,新乡453199

出　　处：《世界中医药》2023年第15期2249-2255,共7页World Chinese Medicine

基　　金：国家自然科学基金面上项目(81573920);河南省中医药科学研究专项课题(2014ZY01020)。

摘　　要：快速性心律失常是一种复杂的生物物理现象,在全世界的发病率和死亡率中占有重要地位。传统抗心律失常药物的安全性受到质疑,微创的侵入式治疗方案术后疗效也不理想。而中药可以多离子通道阻滞、非离子通道调节、多途径、多靶点的整合机制发挥抗心律失常作用,近年来中医药治疗心律失常的研究增多。现以经典方研究为切入点,包括以酸枣仁汤、柴胡加龙骨牡蛎汤、安神定志丸为代表的安神剂;以炙甘草汤、归脾汤、生脉散、小建中汤为代表的补益剂;以黄连温胆汤、泻心汤为代表的清热剂;以血府逐瘀汤为代表的活血化瘀剂;以小柴胡汤、逍遥散为代表的疏肝剂;以及稳心颗粒、参松养心胶囊2味中成药;还有回心草、甘松、人参、莲子心4味中药进行综述。另基于不同的快速型心律失常类型对当今时方研究作简单回顾,以期为临床提供参考。Tachyarrhythmia is a complex biophysical phenomenon with high incidence and mortality worldwide.The safety of conventional antiarrhythmics has been questioned,and minimally invasive treatment is difficult to achieve satisfactory results.Chinese medicines can block multiple ion channels and regulate non-ion channels to play an antiarrhythmic role in a multi-channels and multi-target manner.In recent years,the studies about the treatment of arrhythmia with traditional Chinese medicine have been increasing.This paper reviews the classical Chinese medicinal prescriptions for treating tachyarrhythmia,including the mind-tranquillizing agents represented by Suanzaoren Decoction,Chaihu Longgu Muli Decoction,and Anshen Dingzhi Pills;the tonics represented by Zhigancao Decoction,Guipi Decoction,Shengmai Powder,and Xiaojianzhong Decoction;the heat-clearing agents represented by Huanglian Wendan Decoction and Xiexin Decoction;the blood-activating and stasis-resolving agents represented by Xuefu Zhuyu Decoction;liver-soothing agents such as Xiaochaihu Decoction and Xiaoyao Powder;Chinese patent medicines represented by Wenxin Granules and Shensong Yangxin Capsules;and four Chinese herbal medicines:Rhodobryi Rosei Herba,Nardostachyos Radix et Rhizoma,Ginseng Radix et Rhizoma,and Nelumbinis Plumula.In addition,the current prescriptions used for treating tachyarrhythmia of different syndromes were briefly reviewed.This review aims to provide a reference for clinical practice.

关 键 词：快速性心律失常 心悸 安神剂 补益剂 清热剂 活血化瘀剂 疏肝剂 单味中药 研究进展 

分 类 号：R259[医药卫生—中西医结合]