低温高钠序贯透析联合高渗糖预防透析相关性低血压的疗效观察  

Observation on the effect of low-temperature and high-sodium sequential dialysis combined with hyperosmotic glucose on prevention of dialysis-related hypotension

作　　者：蓝红娟 LAN Hong-juan(Department of Nephrology,Dianbai District People's Hospital,Maoming 525400,China)

机构地区：[1]茂名市电白区人民医院肾内科,525400

出　　处：《中国实用医药》2023年第15期14-18,共5页China Practical Medicine

摘　　要：目的分析长期维持性血液透析患者采用低温高钠序贯透析联合高渗糖预防透析相关性低血压的效果。方法86例长期维持性血液透析患者,随机分为常规透析组(28例)、低温高钠序贯透析组(29例)、低温高钠序贯透析联合高渗糖组(29例)。对比三组透析期间平均动脉压(MAP)变化情况,透析期间并发症发生率,透析后血肌酐、尿素氮、血钾、血钠水平。结果常规透析组、低温高钠序贯透析组、低温高钠序贯透析联合高渗糖组透析中最低MAP分别为(48.56±5.21)、(57.86±6.82)、(76.34±7.26)mm Hg(1 mm Hg=0.133 kPa),透析后MAP分别为(73.36±4.61)、(81.14±4.36)、(88.55±5.56)mm Hg。低温高钠序贯透析联合高渗糖组、低温高钠序贯透析组透析中最低MAP及透析后MAP均高于常规透析组,低温高钠序贯透析联合高渗糖组高于低温高钠序贯透析组,差异具有统计学意义(P<0.05)。低温高钠序贯透析联合高渗糖组的并发症发生率13.79%、低温高钠序贯透析组的并发症发生率37.93%均低于常规透析组的64.29%,低温高钠序贯透析联合高渗糖组的并发症发生率低于低温高钠序贯透析组,差异具有统计学意义(P<0.05)。三组透析后血肌酐、尿素氮、血钾、血钠水平对比,差异无统计学意义(P>0.05)。结论低温高钠序贯透析联合高渗糖治疗能有效预防透析相关性低血压的发生,保证长期维持性血液透析患者的透析质量。与常规透析相比,其可有效预防透析相关性低血压的发生;与低温高钠序贯透析相比,亦不影响透析效果。Objective To analyze the effect of low-temperature and high-sodium sequential dialysis combined with hyperosmotic glucose on prevention of dialysis-related hypotension.Methods A total of 86 patients with long-term maintenance hemodialysis were randomly divided into conventional dialysis group(28 cases),low-temperature and high-sodium sequential dialysis group(29 cases),and low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group(29 cases).The changes of mean arterial pressure(MAP),the incidence of complications during dialysis,and the levels of serum creatinine,urea nitrogen,potassium and sodium after dialysis were compared among the three groups.Results During dialysis,the lowest MAP values in conventional dialysis group,low-temperature and high-sodium sequential dialysis group,and low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group were(48.56±5.21),(57.86±6.82),and(76.34±7.26)mm Hg(1 mm Hg=0.133 kPa),respectively;after dialysis,the MAP were(73.36±4.61),(81.14±4.36),and(88.55±5.56)mm Hg,respectively.The lowest MAP during dialysis and post-dialysis MAP of low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group and low-temperature and high-sodium sequential dialysis group were higher than those of conventional dialysis group;the low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group was higher than the low-temperature and high-sodium sequential dialysis group;the differences were statistically significant(P<0.05).The incidence of complications in the low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group and low-temperature and high-sodium sequential dialysis group were 13.79%and 37.93%,which were lower than that of 64.29%in the conventional dialysis group;the incidence of complications of low-temperature and high-sodium sequential dialysis with hyperosmotic glucose group was lower than that of low-temperature and high-sodium sequential dialysis group;the difference

关 键 词：血液透析 低温高钠 序贯透析 透析相关性低血压 长期维持性血液透析 效果 

分 类 号：R692.5[医药卫生—泌尿科学]