不同性别患者接受股动脉途径经导管主动脉瓣膜置换术的临床相关指标分析  

Analysis of clinical-related indicators of transcatheter aortic valve replacement in patients with different genders

作　　者：安春秀[1] 李娜[1] 纪江霞[1] 赵再仙 蒋博[1] An Chunxiu;Li Na;Ji Jiangxia;Zhao Zaixian;Jiang Bo(Cardiac Intervention Center,First Medical Center,General Hospital of the People's Liberation Army of China,Beijing 100853,China)

机构地区：[1]解放军总医院第一医学中心心脏介入中心,北京100853

出　　处：《血管与腔内血管外科杂志》2023年第7期803-806,819,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨不同性别患者接受股动脉途径经导管主动脉瓣膜置换术的临床相关指标差异。方法收集2020年1月至2023年2月于解放军总医院第一医学中心接受股动脉途径经导管主动脉瓣膜置换术的118例患者的临床资料,按照不同性别将其分为男性组(n=65)和女性组(n=53)。收集并比较两组患者术前的临床特征、化验结果、影像学检查结果及术中相关指标。结果男性组患者的年龄低于女性组患者,但男性组患者的体表面积、吸烟比例、饮酒比例、高血压比例、冠心病比例均高于女性组患者,差异均有统计学意义(P﹤0.05)。术前超声检查结果显示,男性组患者左室射血分数、主动脉瓣平均跨瓣压差均低于女性组患者,差异均有统计学意义(P﹤0.05)。术中,男性组患者使用20 F动脉鞘管比例、置入瓣膜直径、采用球囊后扩张比例均高于女性组患者,差异均有统计学意义(P﹤0.05)。结论不同性别患者接受股动脉途径经导管主动脉瓣置换术的年龄、基础病史、不良嗜好、左室射血分数、主动脉瓣平均跨瓣压差以及手术过程中使用的动脉鞘管型号、瓣膜直径均存在差异,了解不同性别主动脉瓣置换术患者的特点,有利于更好地对患者进行个性化诊治。Objective To investigate the gender differences in patients undergoing femoral access transcatheter aortic valve replacement.Method The clinical data of 118 patients who underwent femoral artery transcatheter aortic valve replacement in the First Medical Center,General Hospital of the People's Liberation Army of China from January 2020 to February 2023 were collected,they were divided into male group(n=65)and female group(n=53)according to different genders.The preoperative clinical characteristics,laboratory results,imaging examination results and intraoperative-related indicators of all patients were collected and compared.Result The age of the male group was lower than that of the female group,while the body surface area,smoking rate,drinking rate,hypertension rate,and coronary heart disease rate of the male group were higher than those of the female group,the differences were statistically significant(P<0.05).The results of preoperative ultrasonography showed that the average left ventricular ejection fraction and the average transvalvular pressure gradient of the aortic valve in the male group were lower than that of the female group,the differences were statistically significant(P<0.05).During the operation,the proportion of 20 F arterial sheath employment,the diameter of the implanted valve,and the proportion of post-dilation balloons in the male group were all higher than those in the female group,the differences were statistically significant(P<0.05).Conclusion There are differences in age,basic medical history,bad habits,left ventricular ejection fraction,mean inter-valve pressure difference of aortic valve,the type of arterial sheath tube used in the operation,and valve diameter of patients with femoral artery artery replacement by different genders.Understanding the characteristics of patients with aortic valve replacement by different genders is beneficial to better personalized diagnosis and treatment of patients.

关 键 词：经导管主动脉瓣膜置换术 股动脉 性别 

分 类 号：R543[医药卫生—心血管疾病]