Synthesis and thermosensitive behavior of dextran graft copolymers containing poly(N-vinylcaprolactam)side chains  

作　　者：SHI Huangying CHEN Wenjuan ZHANG Liming 

机构地区：[1]Institute of Polymer Science,School of Chemistry and Chemical Engineering and Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education,Sun Yat-Sen(Zhongshan)University,Guangzhou 510275,China

出　　处：《Frontiers of Chemical Science and Engineering》2007年第1期72-75,共4页化学科学与工程前沿（英文版）

基　　金：supported by the National Natural Science Foundation of China(Grants No.20676155,No.30470476,No.20273086);Natural Science Foundation of Guangdong Province(Grants No.039184,No.06023103);Department of Science and Technology of Guangdong Province(Grant No.2004B33101003);Program for New Century Excellent Talents in Universities of China(NCET-04-0810).

摘　　要：New graft copolymers were synthesized by graft-ing N-vinylcaprolactam onto dextran.Their composition and structure were investigated by elemental analyses,infrared spectra and thermogravimetric analyses.By optical transmit-tance measurements,it was found that the aqueous solutions of these graft copolymers showed a temperature-dependent transmittance change due to the introduction of thermosensi-tive poly(N-vinylcaprolactam)graft chains.Moreover,the lower critical solution temperature(LCST)of the graft copolymer in aqueous solution was dependent on its grafting extent and concentration.The LCST value was found to increase with the increase of the grafting extent and decrease with the increase of the copolymer concentration.With these stimuli-response properties,such polysaccharide derivative may hold potential applications in biomedicine and biotechnology.

关 键 词：intelligent polymers polysaccharide derivative thermosensitive behavior phase transition 

分 类 号：O63[理学—高分子化学]