0~14岁儿童发育期间垂体形态变化  

Morphological changes of pituitary during development in children aged 0—14 years

作　　者：王驰 陈俊杰 许书聪 孙晶然 白振华[1] 洪天予 闫淯淳 WANG Chi;CHEN Junjie;XU Shucong;SUN Jingran;BAI Zhenhua;HONG Tianyu;YAN Yuchun*(Department of Radiology,Children's Hospital,Capital Institute of Pediatrics,Beijing 100020,China;Department of Radiology,Maternity and Child Health Care of Guangxi Zhuang Autonomous Region,Nanning 530021,China;Imaging Center,National Center for Children's Health,Beijing Children's Hospital,Capital Medical University,Beijing 100045,China)

机构地区：[1]首都儿科研究所附属儿童医院放射科,北京100020 [2]广西壮族自治区妇幼保健院放射科,广西南宁530021 [3]国家儿童医学中心首都医科大学附属北京儿童医院影像中心,北京100045

出　　处：《中国医学影像技术》2023年第8期1124-1128,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察我国0~14岁儿童发育期间垂体形态学变化。方法纳入1400例0~14岁儿童,每岁各100例(男、女各50例);基于头颅3D-T1WI测量腺垂体上下径、前后径、左右径及垂体柄长度,计算其上下径/前后径比值和腺垂体体积,观察垂体各参数与年龄的相关性及其随年龄增长的变化趋势。结果随年龄增长,儿童腺垂体上下径、前后径、左右径及体积基本呈逐渐增大,而垂体柄长度呈减小趋势。男性与女性儿童腺垂体上下径、前后径、左右径,垂体体积及垂体柄长度差异均无统计学意义(P均>0.05)。儿童腺垂体上下径、前后径、左右径及其体积均与年龄呈高度正相关(r均>0.9,P均<0.001),垂体柄高度与年龄呈高度负相关(r>0.9,P<0.001)。结论随年龄增长,0~14岁儿童腺垂体上下径、前后径、左右径及其体积基本呈逐渐增大、而垂体柄长度呈减小趋势。Objective To observe the morphological changes of pituitary during development in children aged 0—14 in China.Methods Totally 1400 children aged from 0 to 14 years were enrolled,with 100 cases(50 males and 50 females)per 1 year old.Based on head 3D-T1WI,the vertical diameter,anteroposterior diameter,left and right diameter and pituitary stalk length of a denohypophysis were measured,and the ratio of vertical diameter to anteroposterior diameter,also the volume of pituitary gland were calculated.The correlations of pituitary parameters with age,and the trends of changes of pituitary parameters with the increase of age were analyzed.Results With the increased of age,the vertical diameter,anteroposterior diameter,left and right diameter as well as the volume of pituitary gland basically increased,while pituitary stalk length decreased.No significant difference of the vertical diameter,anteroposterior diameter,left and right diameter,volume of pituitary gland nor pituitary stalk length was found between male and female children(all P>0.05).The age of children was highly positively correlated with vertical diameter,anteroposterior diameter,left and right diameter and volume of pituitary gland(all r>0.9,all P<0.001),but highly negatively correlated with pituitary stalk length(r>0.9,P<0.001).Conclusion With the increase of age,the vertical diameter,anteroposterior diameter,left and right diameter and volume of pituitary gland basically increased,while pituitary stalk length decreased in children aged 0—14 years.

关 键 词：儿童 垂体 磁共振成像 

分 类 号：R725[医药卫生—儿科]