A cellular automata model for simulating fed-batch penicillin fermentation process  

作　　者：Yu Naigong Ruan Xiaogang 

机构地区：[1]Electronic Information and Control Engineering College,Beijing University of Technology,Beijing 100022,China

出　　处：《Frontiers in Biology》2006年第2期195-202,共8页生物学前沿（英文版）

基　　金：supported by the National Natural Science Foundation of China (No.60274060,60375017);the Key Project of Chinese Ministry of Education (No.203002);Scientific Research Common Program of Beijing Municipal Commission of Education (NO.KM200510005026).

摘　　要：A cellular automata model to simulate penicillin fed-batch fermentation process(CAPFM)was established in this study,based on a morphologically structured dynamic penicillin production model,that is in turn based on the growth mechanism of penicillin producing microorganisms and the characteristics of penicillin fed-batch fermentation.CAPFM uses the three-dimensional cellular automata as a growth space,and a Moore-type neighborhood as the cellular neighborhood.The transition rules of CAPFM are designed based on mechanical and structural kinetic models of penicillin batch-fed fermentation processes.Every cell of CAPFM represents a single or specific number of penicillin producing microorganisms,and has various state.The simulation experimental results show that CAPFM replicates the evolutionary behavior of penicillin batch-fed fermentation processes described by the structured penicillin production kinetic model accordingly.

关 键 词：penicillin fermentation process fermentation dynamics morphologically structured model cellular automata model 

分 类 号：TQ9[化学工程]