血清孕酮联合β-HCG检验对诊断早期先兆流产的临床意义  

Clinical significance of serum progesterone combined with β-HCG test in the diagnosis of early threatened abortion

作　　者：张春暖 Zhang Chunnuan(Department of Clinical Laboratory,The First People's Hospital of Fangchenggang,Fangchenggang 538000,China)

机构地区：[1]防城港市第一人民医院检验科,广西防城港538000

出　　处：《实用妇科内分泌电子杂志》2023年第11期91-93,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究血清孕酮(P)联合β-人绒毛膜促性腺激素(β-HCG)检验对诊断早期先兆流产的临床意义。方法选取200例接受产检的先兆流产孕妇,根据妊娠结局将其分为继续妊娠组(109例)与安胎失败组(91例)。两组均检验P、β-HCG水平,比较两组孕6周、孕8周、孕10周的P、β-HCG水平。结果继续妊娠组孕6周、孕8周、孕10周的血清P水平(34.65±7.58)ng/ml、(39.84±8.42)ng/ml、(45.61±8.29)ng/ml,均明显高于安胎失败组的(28.64±9.23)ng/ml、(33.59±7.28)ng/ml、(37.05±6.38)ng/ml,差异具有统计学意义(P<0.05)。继续妊娠组孕6周、孕8周、孕10周的血清β-HCG水平均明显高于安胎失败组,差异具有统计学意义(P<0.05)。结论早期先兆流产且安胎失败的孕妇P、β-HCG水平较低,临床对这两项指标进行动态监测可以在一定程度上预测先兆流产,为孕妇妊娠结局的判断提供数据支持。Objective To explore the clinical significance of serum progesterone(P)combined with human chorionic gonadotropin(β-HCG)test in diagnosing early threatened abortion.Methods 200 pregnant women with threatened abortion were selected and divided into two groups according to pregnancy outcome,the continued pregnancy group(109 cases)and abortion failure group(91 cases).The levels of P and β-HCG were tested in both groups,and the levels of P and β-HCG at 6 weeks,8 weeks and 10 weeks of pregnancy were compared between the two groups.Results Serum P levels were(34.65±7.58)ng/ml,(39.84±8.42)ng/ml,(45.61±8.29)ng/ml at 6 weeks,8 weeks and 10 weeks of pregnancy in the continued pregnancy group.It was significantly higher than(28.64±9.23)ng/ml,(33.59±7.28)ng/ml and(37.05±6.38)ng/ml in abortion failure group,and the difference was statistically significant(P<0.05).Serum β-HCG levels at 6 weeks,8 weeks and 10 weeks of pregnancy in continued pregnancy group were significantly higher than those in abortion failure group,and the difference was statistically significant(P<0.05).Conclusion Pregnant women with early threatened abortion and abortive failure have low P and β-HCG levels.Clinical dynamic monitoring of these two indicators can predict threatened abortion to a certain extent,and provide data support for the judgment of pregnancy outcome.

关 键 词：先兆流产 孕酮 Β-人绒毛膜促性腺激素 妊娠结局 动态监测 

分 类 号：R714.21[医药卫生—妇产科学]