PRF治疗带状疱疹后神经痛疗效的影响因素分析  

作　　者：沈倩倩[1] 张祖勇 杜忠举[1] 杨志伟 张华[1] 王波[1] 

机构地区：[1]杭州市第三人民医院,310009 [2]杭州市西溪医院,310023

出　　处：《浙江临床医学》2023年第7期1021-1023,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省医药卫生科技计划项目(2021KY251,2023KY963);杭州市科学技术计划项目(20180533B61);杭州市脑病学(中西医结合)重点学科建设项目。

摘　　要：目的筛选脉冲射频术(PRF)治疗带状疱疹后神经痛疗效的影响因素。方法纳入303例PRF治疗的带状疱疹后神经痛患者,使用数字评价量表(NRS)评价疼痛。PRF后3个月NRS评分较术前下降>50%视为治疗有效,并分为有效组和无效组。对组间差异比较有统计学意义的变量进行Logistic回归分析,筛选影响因素。结果PRF治疗带状疱疹后神经痛术后3个月有效率为73.3%,糖尿病(OR=2.179,95%CI=1.052~4.514)、病程(OR=1.823,95%CI=1.556~2.137)、射频电压(OR=0.435,95%CI=0.217~0.872)、射频神经(OR=0.421,95%CI=0.209~0.849)与PRF治疗带状疱疹后神经痛的疗效存在相关性。结论糖尿病和病程是PRF治疗带状疱疹后神经痛疗效的独立危险因素;高射频电压、3个射频神经为PRF疗效的有利因素。Objective To screen the influence factors for efficacy after pulsed radiofrequency in patients with postherpetic neuralgia.Methods A total of 303 patients with postherpetic neuralgia(PHN)undergoing pulsed radiofrequency(PRF)were included.The perioperative indicators were observed and pain degree was assessed by the numerical rating scale(NRS).We defined the effectiveness at 3months after PRF for PHN as relief of>50%in NRS scores compared to pre-PRF,and patients were divided into the positive group and the negative group.The general data between the two groups were compared and logistic analysis was performed to screen for the influence factors.Results The PRF effective rate after 3months was 73.7%.Diabetes(OR=2.179,95%CI=1.052~4.514),disease duration(OR=1.823,95%CI=1.556~2.137),PRF voltage(OR=0.435,95%CI=0.217~0.872),PRF nerves(OR=0.421,95%CI=0.209~0.849)were correlated with PRF efficacy in patients with postherpetic neuralgia.Conclusion Diabetes and disease duration were the risk factors for PRF effectiveness,the high PRF voltage and 3 PRF nerves were favorable factors.

关 键 词：带状疱疹后神经痛 脉冲射频 疗效 影响因素 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]