神经外科患者非导管相关性血流感染的临床特点与危险因素分析  

作　　者：俞晓翔[1] 王耿焕[1] 张李涛[1] 褚正民[1] 沈和平[1] 

机构地区：[1]嘉兴学院附属第二医院,314000

出　　处：《浙江临床医学》2023年第7期1024-1026,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省医药卫生科技计划(2022KY1257);浙江省医学会临床科研基金项目(2021ZYC-A150);浙江省嘉兴市科技计划项目(2019AD32138)。

摘　　要：目的探讨神经外科患者发生非导管相关性血流感染的临床特点及危险因素分析。方法回顾性分析本院神经外科发生血流感染121例患者的临床资料,采用多因素Logistic回归分析非导管相关性血流感染的危险因素。结果73例患者发生非导管相关性血流感染,继发于其他部位感染70例,未明确原因3例,死亡41例,死亡率56.2%。革兰氏阴性菌是最常见的病原体。多重耐药菌58例,占79.5%,多因素Logistic回归分析显示,严重低白蛋白血症、颅内感染、呼吸机相关性肺炎(VAP)差异有统计学意义(P<0.05)。结论非导管相关性血流感染多为继发性血流感染,多重耐药菌比例高,死亡率高,严重低白蛋白血症、颅内感染、VAP是非导管相关性血流感染的独立危险因素。Objective To explore the clinical characteristics and risk factors of non-catheter-related bloodstream infections in neurosurgery patients.Methods A retrospective analysis of the clinical data of 121 patients with bloodstream infections in the department of neurosurgery in our hospital was performed.Multivariate logistic regression was used to analyze the risk factors of non-catheter-related bloodstream infections.Results Non-catheter-related bloodstream infections occurred in 73 patients.70 cases were clearly secondary to infections at other sites,but no clear cause was found in 3 cases.41 cases died,with a mortality rate of 56.2%.Gram-negative bacteria were the most common pathogen.There were 58 cases of multidrug-resistant bacteria,accounting for 79.5%.Multivariate Logistic regression analysis showed that severe hypoproteinemia,intracranial infections and VAP were statistically significant(P<0.05).Conclusion Non-catheter-related bloodstream infections were mostly secondary bloodstream infections,with a high proportion of multidrug-resistant bacteria,high mortality.Severe hypoproteinemia,intracranial infections,and VAP are independent risk factors for non-catheter-related bloodstream infections.

关 键 词：神经外科 导管相关性血流感染 危险因素 

分 类 号：R47[医药卫生—护理学]