超重或肥胖患者QT、QTc、PR间期与动脉粥样硬化相关性分析  

作　　者：李莉[1] 

机构地区：[1]浙江绍兴绍兴第二医院医共体总院,312000

出　　处：《浙江临床医学》2023年第7期1043-1045,共3页Zhejiang Clinical Medical Journal

摘　　要：目的分析超重或肥胖患者QT、QTc、PR间期与动脉粥样硬化(AS)的相关性。方法选取超重或肥胖体检者202例,根据有无颈动脉粥样硬化(CAS)分为两组,收集临床基本资料及辅助检查结果,对其进行统计学分析。结果有CAS组QT间期、校正QT(QTc)间期、PR间期、收缩压、空腹血糖(FPG)、糖化血红蛋白(HbA1C)、谷草转氨酶(AST)、甘油三酯(TG)、氨酰转肽酶(GGT)、血肌酐(Scr)、白细胞数(WBC)、谷丙转氨酶(ALT)、有脂肪肝者的占比、ECG异常者占比高于无CAS组,总胆红素(TBIL)低于无CAS组;QTc间期与收缩压、WBC及QT间期呈正相关;TG、PR间期、QTc间期、GGT是超重或肥胖人群发生CAS的独立危险因素。结论超重或肥胖人群QT、QTc、PR间期延长与CAS相关,有CAS个体的血糖、血脂及肝肾功能等指标也有所上升。Objective To observe the correlation between QT,QTc,PR and atherosclerosis(AS)in overweight or obese patients.Methods 202 overweight or obese patients in our hospital were selected and divided into groups according to whether they had carotid atherosclerosis(CAS).Their general condition and supplementary examination results were collected and statistically analyzed.Results The QT interval,QTc interval,PR interval,SBP,FPG,HbA1C,TG,Scr,GGT,AST,ALT,WBC,proportion of patients with fatty liver and abnormal ECG in A group were higher than those in C group,but TBIL was reversed.QTc interval was positively correlated with SBP,WBC and QT interval.TG,PR interval,QTc interval and GGT were independent risk factors for CAS in overweight or obese people.Conclusion The prolongation of QT,QTc and PR interval in overweight or obese patients is related to CAS,and the blood glucose,blood lipid,liver function and kidney function of these patients with CAS are also increased.

关 键 词：肥胖 动脉粥样硬化 QT间期 QTC间期 PR间期 

分 类 号：R543.5[医药卫生—心血管疾病]