功能化聚芳醚酮固载铜离子抑菌膜制备及表征  

Preparation and characterization of copper ion loaded functionalpoly(arylene ether ketone) antibacterial membranes

作　　者：胡淑倩 丁辉 金伟 黎姗姗 张浩[1] 王建黎[1] HU Shuqian;DING Hui;JIN Wei;LI Shanshan;ZHANG Hao;WANG Jianli(Department of Chemical Engineering,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]浙江工业大学化学工程学院,浙江杭州310014

出　　处：《高校化学工程学报》2023年第4期633-642,共10页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金(22178317,22109138)。

摘　　要：为了使微孔滤膜具有抑菌功能,以自制的侧链含苯并咪唑结构聚芳醚酮为膜材料,利用苯并咪唑基团与Cu^(2+)间的配位作用,通过非溶剂致相分离法(NIPS)和金属离子配位改性法制备抑菌型微孔滤膜。对固载Cu^(2+)前后的微滤膜的微观结构、抗污性能、抑菌性能、耐溶剂性能以及膜的Cu^(2+)固载量等进行测试与表征。结果表明,Cu^(2+)能够被固载至含有苯并咪唑结构的微孔滤膜上。所制备的Cu^(2+)螯合膜对大肠杆菌的抑制率可达63%,且随着开孔率的增加,膜的抑菌性能有所提升。其中,抑菌圈实验和Cu^(2+)流失速率测试实验进一步说明了Cu^(2+)与聚合物分子链上的苯并咪唑基团间的相互作用能够将Cu^(2+)约束在膜内,有效缓解金属离子流失现象。In order to provide microporous membranes with antibacterial functions,self-made poly(arylene ether ketone)with benzimidazole side groups that can coordinate with Cu^(2+)was chosen as membrane material.The antibacterial microporous membranes were prepared by non-solvent-inducing phase separation(NIPS)and metal ion coordination modification methods.Microstructure,fouling resistance,antibacterial effect,solvent resistance and immobilized Cu^(2+)contents were characterized.The results indicate that Cu^(2+)can be successfully immobilized into the microporous membrane containing benzimidazole groups.The antibacterial rate to Escherichia coli reached 63%,and the antibacterial performance was improved with the increase of aperture ratio.Inhibition zone experiments and Cu^(2+)release rate tests further demonstrate that the interaction between Cu^(2+)and benzimidazole groups restrained Cu^(2+)in the membrane,which effectively alleviates the loss of metal ions.

关 键 词：抑菌膜 过渡金属离子 苯并咪唑基团 配位交联 

分 类 号：TQ028.8[化学工程]