扩散磁共振图像的大脑微结构成像研究综述  

Review of Brain Microstructural Imaging with Diffusion Magnetic Resonance Imaging

作　　者：朱悦敏 王远军[1] ZHU Yue-min;WANG Yuan-jun(Institute of Medical Imaging Technology,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]上海理工大学医学影像技术研究所,上海200093

出　　处：《小型微型计算机系统》2023年第8期1763-1770,共8页Journal of Chinese Computer Systems

基　　金：上海市自然科学基金项目(18ZR1426900)资助。

摘　　要：微结构成像是基于扩散磁共振成像在活体内表征人脑组织微结构特性的技术,现已被广泛应用于神经科学研究和临床应用中.微结构成像模型将不同组织特性和磁共振信号相关联以估算组织的微观特性,本文首先介绍微结构成像的研究现状及不足,之后从信号模型与多隔室模型两个角度综述了经典的大脑微结构成像方法,总结这两类模型存在的优点及不足,并介绍微结构量化分析方法,最后对微结构成像技术进行总结和展望.Microstructure imaging is a technique based on diffusion magnetic resonance imaging to characterize the microstructure of human brain tissue in vivo.It has been widely used in neuroscience research and clinical application.The microstructure imaging model correlates different tissue properties and magnetic resonance signals to estimate the microscopic properties of the tissue.This paper first introduces the research status and shortcomings of microstructure imaging,then summarizes the classical brain microstructure imaging methods from the perspective of signal model and multi compartment model,summarizes the advantages and disadvantages of these two types of models,and introduces the quantitative analysis methods of microstructure.Finally,the microstructure imaging technology is summarized and prospected.

关 键 词：扩散磁共振成像 微结构成像 信号模型 多隔室模型 

分 类 号：TP391[自动化与计算机技术—计算机应用技术]