艾司氯胺酮对无痛人工流产术女性生命体征与舒适度的改善作用  

Effect of esketamine for improvement of vital signs and comfort of women in painless sugical abortion

作　　者：张亚男 刘禹含[1] 马晓婧 ZHANG Yanan;LIU Yuhan;MA Xiaojing(Daxing District People's Hospital,Beijing,102600;The First Medical Center of the Chinese People's Liberation Army General Hospital,Beijing)

机构地区：[1]北京市大兴区人民医院,102600 [2]中国人民解放军总医院第一医学中心

出　　处：《中国计划生育学杂志》2023年第8期1802-1806,共5页Chinese Journal of Family Planning

摘　　要：目的:分析艾司氯胺酮对无痛人工流产手术者生命体征与舒适度的改善作用。方法:将2021年1月-2023年1月在本院妇产科拟行无痛人工流产手术者100例随机分成对照组与观察组各50例,分别静脉注射舒芬太尼0.1μg/kg或艾司氯胺酮0.1~0.2mg/kg+丙泊酚2mg/kg。观察麻醉指标、生命体征、术后宫缩痛程度(VAS评分)、术后舒适度(GCQ评分)、不良反应。结果:观察组麻醉指标优于对照组,静脉注射丙泊酚后、术毕时生命体征优于对照组;苏醒后10、20、30、60min的宫缩痛VAS评分(2.98±0.50分、2.14±0.41分、2.00±0.35分、1.35±0.16分)均低于对照组(3.47±0.53分、2.73±0.36分、2.42±0.27分、2.00±0.24分),舒适度GCQ评分(89.98±9.56分、94.72±11.68分、100.33±12.41分、105.62±11.04分)均高于对照组(84.57±10.73分、88.69±12.59分、95.72±12.73分、99.14±10.45分),不良反应发生率(6.0%)低于对照组(20.0%)(P<0.05)。结论:艾司氯胺酮联合丙泊酚在无痛人工流产手术中效果较好,可改善麻醉指标、促进术后苏醒、稳定生命体征,减轻术后宫缩痛,提高术后舒适度,降低不良反应,有效性与安全性均较好。Objective:To analyze the efect of esketamine used for the improvement of vital signs and comnfort of women in painless sugical abortion.Methods:From January 2021 to January 2023,100 women who wanted painless sugical a-bortion were randomly divided into two groups(50 cases in each group).The women in the control group were given sufentanil 0.1 pug/kg combined with propofol 2 mg/kg injection intravenously.and the women in the observation group were given esketamine 0.1-0.2 mg/kg combined with propofol 2 mg/kg injection intravenously.The values of the anes-thesia indexes,the vital signs,the degree of postoperative uterine contraction pain by VAS score,the postoperative comfort by GCQ score,and the adverse reactions rate of the women in the two groups were observed.Results:The an-esthesia indexes values of the women in the observation group were significantly better than those of the women in the control group,and the wital signs of the women in the observation group after propofol intravenous injection and after the operation were significantly better than those of the women in the control group.The VAS scores of uterine con-traction pain of the women in the observation group at 10min,20min,30min,and 60min after awakening were 2.98±0.50 points,2.14±0.41 points,2.00±0.35 points,and 1.35±0.16 points,respectively,which were significantly lower than those(3.47±0.53 points,2.73±0.36 points,2.42±0.27 points,and 2.00±0.24 points,respectively)of the women in the control group.The comfort GCQ scores of the women in the observation group at 10min.20min,30min.and 60min after awakening were 89.98±9.56 points.94.72±11.68 points,100.33±12.41 points.and 105.62±11.04 points,respectively,which were significantly higher than those(84.57±10.73 points,88.69±12.59,95.72±12.73,and 99.14±10.45 points,respectively)of the women in the control group.The incidence of adverse reactions(6.0%)was significantly lower than that(20.0%)of the women in the control group(P<0.05).Conclusion:Esketamine combined with propofol used in pain

关 键 词：无痛人工流产手术 艾司氯胺酮 丙泊酚 生命体征 舒适度 宫缩痛 不良反应 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]