机构地区:[1]浙江省湖州市中医院,313000
出 处:《中国计划生育学杂志》2023年第8期1844-1848,共5页Chinese Journal of Family Planning
基 金:湖州市科学技术项目(2020GYB12)。
摘 要:目的:探究针刺与中药汤剂联合治疗多囊卵巢综合征(PCOS)效果。方法:选取2019年11月-2022年11月本院收治的PCOS患者138例,随机分为针药组和西药组各69例,分别采用针刺联合中药汤剂治疗或枸橼酸氯米芬片口服治疗,对比两组疗效、性激素水平、内脂素(Visfatin)、鸢尾素(Irisin)、卵巢功能、简易生活质量(SF-36)评分及不良反应发生率。结果:治疗总有效率针药组(88.4%)高于西药组(72.5%),黄体生成素(7.19±2.01 U/L)、Visfatin(16.30±4.14 ng/ml)、Irisin(165.44±10.41μg/L)低于西药组(10.16±2.42 U/L、19.89±3.29 ng/ml、184.54±11.70μg/L),窦卵细胞数(4.34±0.42个)、卵巢积液(6.93±0.44 ml)、子宫粘液评分(55.24±4.34分)低于西药组(7.05±0.41个、8.51±0.31 ml、63.23±3.14分),子宫内膜厚度(8.90±0.52mm)高于西药组(7.18±0.42mm),SF-36评分(647.54±26.11分)高于西药组(436.72±18.63分)(均P<0.05);不良反应发生率两组(8.7%、11.6%)无差异(P>0.05)。结论:针药结合治疗PCOS可有效改善患者激素水平及卵巢功能,提高生活质量,安全性较好。Objective:To explore the eficacy of the combination of acupuncture and traditional Chinese medicine decoc-tion for treating patients with polycystic ovary syndrome on(PCOS).Methods:A total of 138 patients with PCOS were included and were randomly divided into two groups from November 2019 to November 2022.The patients in the study group were treated with acupuncture combined with traditional Chinese medicine decoction,while the patients in the control group were treated with acupuncture combined with clomiphene citrate tablets.The efficacy.the levels of sex hormone,visfatin,and irisin,the ovarian function,the score by simple quality of life assesstment form(SF-36),and the incidence of adwerse reactions of the patients were compared between the two groups.Results:The total effec-tive rate(88.4%)of the patients in the study group was significantly higher than that(72.5%)of the patients in the control group.The levels of luteinizing hormone(7.19±2.01 U/L),visfatin(16.30±4.14 ng/ml),and irisin(165.44±10.41μg/L)of the patients in the study group were significantly lower than those(10.16±2.42 U/L,19.89±3.29 ng/ml,and 184.54±11.70pg/L)of the patients in the control group.The number of sinus eggs(4.34±0.42),the o-varian effusion(6.93±0.44 ml),and the uterine mucus score(55.24±4.34 points)of the patients in the study group were significantly lower than those(7.05±0.41,8.51±0.31 ml,and 63.23±3.14 points)of the patients in the control group.The endometrial thickness(8.90±0.52mm)and the SF-36 score(647.54±26.11 points)of the patients in the study group were significantly higher than those(7.18±0.42mm and 436.72±18.63 points)of the patients in the con-trol group(all P<0.05).There was no significant difference in the incidence of adverse reactions(8.7%vs.11.6%)of the patients between the two groups(P>0.05).Conclusion:The combination of acupuncture and traditional Chinese medicine decoction for PCOS can effectively increase the hormones levels and the ovarian function,and improve the quality of lifte,with bette
关 键 词:多囊卵巢综合征 针灸 中药汤剂 卵巢功能 性激素 内脂素 生活质量
分 类 号:R271.9[医药卫生—中西医结合]
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