血清β-hCG水平与异位妊娠发生概率分析  

Analysis of the serum β- human chorionic gonadotropin level of pregnant women and the probability of their ectopic pregnancy occurrence

作　　者：耿鸽 胡庆贺 GENG Ge;HU Qinghe(The First People's Hospital of Huoqiu County,Lu'an,Anhui Province,237400)

机构地区：[1]安徽省霍邱县第一人民医院,237400

出　　处：《中国计划生育学杂志》2023年第8期1901-1907,共7页Chinese Journal of Family Planning

摘　　要：目的:分析不同血清人绒毛膜促性腺激素(β-hCG)水平孕妇异位妊娠发生情况。方法:回顾性收集2017年9月-2022年9月本院就诊的异位妊娠孕妇85例为异位妊娠组,正常宫内妊娠85例为非异位妊娠组。对比分析两组临床资料及血清β-hCG水平,多因素logistic回归分析影响异位妊娠发生的危险因素。根据β-hCG水平分组,采用潜在类别分析法比较不同组间危险因素分布。结果:盆腔炎症、妊娠次数多、人工流产次数、异位妊娠史、盆腔手术史、剖宫产史、宫内节育器避孕史、血清β-hCG<1500U/L均为发生异位妊娠的独立危险因素,血清β-hCG水平降低异位妊娠发生概率上升;聚类分析显示,β-hCG<1500U/L组异位妊娠发生率(76.5%)高于β-hCG≥1500U/L组(25.8%),危险因素较多型占比高于β-hCG≥1500U/L组(均P<0.05)。结论:不同血清β-hCG水平孕妇异位妊娠发生几率有差异,血清β-hCG<1500U/L及危险因素较多者发生异位妊娠概率增加。Objective:To analyze the occurrence of ectopic pregnancy of pregnant women with different levels of serum.βhuman chorionic gonadotropin(β-hCG).Methods:85 pregnant women with ectopic pregnancy in study group and 85 normal in control group pregnant women from September 2017 to September 2022 were collected retrospectively.The clinical data and the serumβ-hCG level of the women were compared between the two groups.Multivariate logistic re-gression analysis was used to analyze the risk factors of ectopic pregnancy.These women were further divided different groups according to theirβ-hCG level,and potential category analysis was used to compare the distributions of the risk factors of the ectopic pregnancy occurrence of the women among the different groups.Results:The pelvic inflammation history,the number of pregnancies,the number of induced abortion,the history of ectopic pregnancy,the history of pelvic surgery,the history of cesarean section,the history of intrauterine device used,the serumβ-hCG level <1500U/L of the pregnant women were all the independent risk factors of their ectopic pregnancy occurrence.The prob-ability of ectopic pregnancy occurrence of the women had increased with the decrease of their serum 8-hCG level.Clus-ter analysis showed that the incidence of ectopic Pregnancy(76.5%)of the women withβbhCG level<1500U/L was significantly higher than that(25.8%)of the women withβ-hCG level≥1500U/L,and the proportion of more risk factors of ectopic pregnancy the women withβ-hCG level<1500U/L was significantly higher than that of the women withβ-hCG level≥1500U/L(all P<0.05).Conclusion:The probability of ectopic pregnancy occurrence of the preg-nant women with different level of serumβ-hCG has variant.The probability of ectopic pregnancy occurrence of the pregnant women with serumβ:-hCG level<1500U/L or the pregnant women with more risk factors has increased.

关 键 词：异位妊娠 人绒毛膜促性腺激素 影响因素 

分 类 号：R714.22[医药卫生—妇产科学]