醋红大戟的质量标准研究  

Study on the quality standard of vinegar-processed Knoxiae Radix

作　　者：陈曦 高燕[2] 王杨海 贾明倩 张悦 马露兰 赵渤年 CHEN Xi;GAO Yan;WANG Yanghai;JIA Mingqian;ZHANG Yue;MA Lulan;ZHAO Bonian(School of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Innovation Institute of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东中医药大学药学院,山东济南250355 [2]山东中医药大学中医药创新研究院,山东济南250355

出　　处：《山东科学》2023年第4期18-28,共11页Shandong Science

基　　金：山东省中药材及饮片标准研究项目(ZYYCX20200001);醋红大戟的质量标准研究起草项目(2020-091)。

摘　　要：对醋红大戟的质量标准进行全面研究,为制定该品种的《山东省中药饮片炮制规范》标准提供技术支撑。在《山东省中药饮片炮制规范》2012年版醋红大戟质量标准的基础上,收集红大戟样品29批次,醋制加工后,对醋红大戟的性状、水分、总灰分、酸不溶性灰分、醇溶性浸出物、显微、薄层、含量测定进行了系统研究和分析,制定相关限度。在原有标准基础上增加了显微鉴别项、芦西定含量测定项,修订了浸出物项,完善了该饮片的质量标准。该研究确定了醋红大戟的质量控制指标,所建立的质量控制方法操作方便、重复性好、结果准确,可用于控制醋红大戟的质量。The study aimed to conduct a comprehensive study on the quality requirements for Knoxiae Radix processed with vinegar and to offer technical support for the formulation of the standard of Shandong Province Chinese herbal medicine processing specification.On the basis of the quality standard of vinegar-processed Knoxiae Radix in Shandong Province Chinese herbal medicine processing specification(2012),29 batches of Knoxiae Radix samples were collected.Following vinegar processing,the parameters including characteristics,moisture,total ash,acid insoluble ash,alcohol soluble extract content,microscopic,and thin layer and content determination were systematically studied and analyzed and the relevant limits were formulated.The project was established on the basis of the current quality standard,in which the microscopic identification,and the lucidin content determination were added,and the extractum item were revised when compared with current quality standard.This study established the Knoxiae Radix quality control index after vinegar processing.The established method of quality control is simple,reproducible,and accurate which can be used for quality control of vinegar-processed Knoxiae Radix.

关 键 词：醋红大戟 鉴别 质量标准 芦西定 含量测定 

分 类 号：R284.1[医药卫生—中药学]