197例己酮可可碱注射液医嘱点评分析与医院合理用药监管模式探讨  

Analysis of 197 cases of pentoxifylline injection and exploring supervision mode of rational drug use in hospitals

作　　者：陈群 朱和平 袁小龙 CHEN Qun;ZHU Heping;YUAN Xiaolong(Department of pharmacy,Wuhu Hospital of Traditional Chinese Medicine,Wuhu 241000,Anhui,China;Department of Pharmacy,the Second Affiliated Hospital ofWannan Medical College,Wuhu 241000,Anhui,China)

机构地区：[1]芜湖市中医医院药剂科,安徽芜湖241000 [2]皖南医学院第二附属医院药剂科,安徽芜湖241000

出　　处：《中国临床药理学与治疗学》2023年第8期948-953,共6页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：安徽省教育厅高等学校自然科学研究项目(KJ2017A248)。

摘　　要：目的:分析和点评某院使用己酮可可碱注射液的情况,探讨有效监管模式,为其在临床合理使用提供参考。方法:利用HIS系统随机抽取出院日期在2021年10月至2022年6月使用己酮可可碱注射液的住院患者病历,共197例。参考说明书以及收集循证医学证据,评价己酮可可碱注射液在该院临床使用的合理性。结果:在抽取的197例病历中,不合理病历140例,占总病历71.07%,其中,无适应证用药111例(79.29%),超说明书用药13例(9.29%),适应证不适宜2例(1.43%),用法用量不适宜13例(9.29%),溶媒选择不适宜1例(0.71%)。结论:该院己酮可可碱注射液的使用存在较严重不合理现象,需通过智慧药学管理模式、建立健全制度、加强用药宣教等方式干预,规范其临床应用。AIM:To analyze and evaluate the use of pentoxifylline injection in a hospital,and explore effective supervision mode,so as to provide some reference for clinical rational drug use.METHODS:A total of 197 inpatients with pentoxifylline injection who were discharged from October 2021 to June 2022 were randomly selected from HIS system.Referring to drug-label and collecting evidence-based medical evidence to judge the rationality of use of pentoxifylline injection in the hospital.RESULTS:Among the 197 medical records extracted,140 medical records were unreasonable,accounting for 71.07%of the total medical records.Among them,111 cases(79.29%)were no indication for use,13 cases(9.29%)were off-label,2 cases(1.43%)were inappropriate for indications,13 cases(9.29%)were inappropriate for usage and dosage,and 1 case(0.71%)was inappropriate for solvent.CONCLUSION:The irrational use of pentoxifylline injection in this hospital is serious.It is necessary to standardize its clinical application through the intervention of smart pharmacy management mode,improving system,strengthening medication education and other ways.

关 键 词：己酮可可碱注射液 合理用药 医嘱点评 监管模式 

分 类 号：R97[医药卫生—药品]