早期俯卧位通气在小儿脓毒症合并急性呼吸窘迫综合征中的应用效果  

Effect of Early Prone Position Ventilation in Children with Sepsis Complicated with Acute Respiratory Distress Syndrome

作　　者：郭红 Guo Hong(Liupanshui Maternal and Child Health Hospital of Guizhou Province,Liupanshui 553000,China)

机构地区：[1]贵州省六盘水市妇幼保健院,贵州六盘水553000

出　　处：《中外医药研究》2023年第9期36-38,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探究早期俯卧位通气干预在脓毒症合并急性呼吸窘迫综合征患儿中的应用效果。方法:选取2020年1月—2023年1月贵州省六盘水市妇幼保健院收治的脓毒症合并急性呼吸窘迫综合征患儿44例为观察对象,依据随机数字表法分为观察组和对照组,各22例。两组均在常规气管插管机械通气的同时采用俯卧位通气干预,对照组于开始使用呼吸机24 h后实施俯卧位通气,观察组于开始使用呼吸机6 h内实施俯卧位通气。比较两组临床指标水平、机械通气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、PaO_(2)与吸入氧浓度比值(PaO_(2)/FiO_(2))]水平。结果:观察组干预后心率、气道平台压低于对照组,机械通气时间短于对照组,差异有统计学意义(P<0.001);干预后,观察组PaO_(2)、PaO_(2)/FiO_(2)高于对照组,PaCO_(2)低于对照组,差异有统计学意义(P<0.001)。结论:小儿脓毒症合并急性呼吸窘迫综合征患儿机械通气时,采用早期俯卧位通气干预,可改善血气指标及呼吸症状。Objective:To investigate the effect of early prone ventilation intervention in children with sepsis complicated with acute respiratory distress syndrome.Methods:A total of 44 children with sepsis combined with acute respiratory distress syndrome admitted to Liupanshui Maternal and Child Health Hospital of Guizhou Province from January 2020 to January 2023 were selected as the observation objects,and were divided into observation group and control group according to random number table method,with 22 cases in each group.Prone position ventilation was used in both groups along with routine tracheal intubation mechanical ventilation.The control group was given prone position ventilation 24 hours after the start of ventilator,and the observation group was given prone position ventilation within 6 hours after the start of ventilator.The level of clinical indexes and mechanical ventilation indexes[partial pressure of arterial oxygen(PaO_(2)),partial pressure of arterial carbon dioxide(PaCO_(2)),ratio of PaO_(2) to inhaled oxygen concentration(PaO_(2)/FiO_(2))]were compared between the two groups.Results:After intervention,the heart rate and airway platform of observation group were lower than control group,and the mechanical ventilation time was shorter than control group,the difference was statistically significant(P<0.001);After the intervention,PaO_(2) and PaO_(2)/FiO_(2) in the observation group were higher than those in the control group,and PaCO_(2) was lower than those in the control group,with statistical significance(P<0.001).Conclusion:Early prone ventilation intervention can improve blood gas index and respiratory symptoms in children with sepsis complicated with acute respiratory distress syndrome.

关 键 词：小儿脓毒症 急性呼吸窘迫综合征 俯卧位机械通气 氧合指数 

分 类 号：R47[医药卫生—护理学]