清咽滴丸质量研究和抗病毒作用的研究进展  

Research progress in quality studies and antiviral effect of Qingyan Dropping Pills

作　　者：王玉丽 张铭芮 周鸿 周学海 李遇伯[7] 李虎玲 商丹丹 王金磊 黄鹤[2] 王一涛[8] 刘昌孝 Wang Yuli;Zhang Mingrui;Zhou Hong;Zhou Xuehai;Li Yubo;Li Huling;Shang Dandan;Wang Jinlei;Huang He;Wang Yitao;Liu Changxiao(Tianjin Pharmaceutial DA REN TANG Group Corporation Limited Traditional Chinese Pharmacy Research Institutet,Tianjin 300457,China;Key Laboratory of Systems Bioengineering(Ministry of Education),School of Chemistry Engineering and Technology,Tianjin University,Tianjin 300072,China;Tianjin Key Laboratory of Quality Control in Chinese Medicine,Tianjin 300457,China;Tianjin Pharmaceutical Holdings,Tianjin 300012,China;'Tianjin Pharmaceutial DA REN TANG Group Corporation Limited Traditional,Tianjin 300190,China;Tianjin Pharmaceutial DA REN TANG Group Corporation Limited Traditional The Sixth Traditional Chinese Medicine Factory,Tianjin 300401,China;Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Chinese Academy of Traditional Chinese Medicine,University of Macao,Macao 519000,China;Tianjin Binhai Research Center for Food and Drug Regulatory Science,Tianjin 300462,China)

机构地区：[1]津药达仁堂集团股份有限公司中药研究院,天津300457 [2]天津大学化学工程与技术学院,系统生物工程教育部重点实验室,天津300072 [3]天津市中药质量控制企业重点实验室,天津300457 [4]天津医药集团股份有限公司,天津300012 [5]津药达仁堂集团股份有限公司,天津300190 [6]津药达仁堂集团股份有限公司第六中药制药厂,天津300401 [7]天津中医药大学,天津301617 [8]澳门大学中华中医药研究院,中国澳门519000 [9]释药技术与药代动力学国家重点实验室,中药质量标志物国家重点实验室,天津300462

出　　处：《国际生物医学工程杂志》2023年第3期258-263,共6页International Journal of Biomedical Engineering

摘　　要：清咽滴丸具有疏风清热、解毒利咽的功效,在临床上常用于治疗急慢性咽炎、咽痛和咽干,是治疗咽喉类疾病的常用中成药。随着新型冠状病毒肺炎(COVID-19)疫情进入后疫情时代,新型冠状病毒肺炎及其症状的常态化用药成为新的趋势,因此挖掘和开发具有抗病毒作用的中成药具有很好的应用前景。清咽滴丸药材组方、物质基础及前期研究发现其具有抗病毒的应用潜力,主要从清咽滴丸质量研究和抗病毒作用等方面的研究进展进行梳理,探讨其二次开发的研究方向,为传统中药的老药新用提供思路和参考。Qingyan Dropping Pills have the effects of relieving wind and heat,detoxifying,and promoting the pharynx.It is commonly used in traditional Chinese medicines to treat acute and chronic pharyngitis,as well as sore throats and dry throats caused by surgery.Recently,many studies have shown that Qingyan Dropping Pills have certain effects on bacteriostasis,anti-inflammatory,antioxidant,and antiviral activities.As the coronavirus disease 2019(COVID-19)pandemic enters the post-epidemic era,the regular use of drugs for COVID-19 pandemic symptoms has become a new trend.Therefore,there is a good market prospect to explore and develop Chinese patent medicines with antiviral effects.A preliminary study on the herbal formula and material basis of Qingyan Dropping Pills revealed that they have potential for antiviral applications.In this paper,the research on the quality study and antiviral effect of Qingyan Dropping Pills was reviewed,and the research direction of its secondary development was discussed to provide ideas and references for the new use of old traditional Chinese medicines.

关 键 词：清咽滴丸 物质基础 药理作用 质量研究 抗病毒 

分 类 号：R286[医药卫生—中药学]