人类免疫缺陷病毒感染孕产妇母婴阻断治疗依从性调查及相关影响因素分析  

Investigation of compliance and analysis of related influencing factors of maternal and infant block therapy in pregnant women infected with human immunodeficiency virus

作　　者：卜霄 BU Xiao(Department of Maternity Group Health Care,Jinhua Maternal and Child Health Hospital,Jinhua,Zhejiang 321000,China)

机构地区：[1]金华市妇幼保健院孕产群体保健科,浙江金华321000

出　　处：《中国妇幼保健》2023年第16期3059-3063,共5页Maternal and Child Health Care of China

基　　金：浙江省医药卫生科技计划项目(2022KY1334)。

摘　　要：目的分析人类免疫缺陷病毒(HIV)感染孕产妇母婴阻断治疗依从性及相关影响因素。方法选取2022年1月—10月在金华市疾控中心连续筛选感染HIV孕妇100例为研究对象,对所纳入患者一般资料进行调查,对患者治疗药物分布情况、治疗依从性及影响因素进行调查分析。结果100例患者中,依从性差患者14例,占比14.00%,依从性良好患者86例,占比86.00%;多因素logistic回归分析结果显示,HIV感染孕产妇母婴阻断治疗依从性影响因素包括知情选择、生育产次、方案复杂及治疗信心(χ^(2)=8.871、6.487、10.782及5.247,均P<0.05)。结论HIV感染孕产妇母婴阻断治疗期间,产妇依从性存在较差情况,影响因素包括知情选择、生育产次、方案复杂及治疗信心,加强治疗期间影响因素干预,可提高依从性,进而影响患者阻断治疗效果。Objective To analyze the compliance of mother-to-child blocking therapy and related influencing factors in pregnant women infected with human immunodeficiency virus(HIV).Methods 100 HIV-infected pregnant women were selected from Jinhua Cen⁃ter for Disease Control and Prevention from January to October 2022.General data of the included patients were investigated,and the distribu⁃tion of therapeutic drugs,treatment compliance and influencing factors of the patients were investigated and analyzed.Results Among 100 patients,there were 14 patients with poor compliance,accounting for 14.00%,and 86 patients with good compliance,accounting for 86.00%;Multivariate logistic regression analysis showed that the influencing factors for compliance of HIV-infected pregnant women with MCT included informed choice,birth number,complexity of plan and confidence in treatment(χ^(2)=8.871,6.487,10.782 and 5.247,P<0.05).Conclusion During the treatment of mother-to-child blocking therapy for HIV-infected pregnant women,the maternal compliance is poor,and the influencing factors include informed choice,birth number,complicated plan and confidence in treatment.Strengthening the intervention of influencing factors during the treatment can improve the compliance,and then affect the effect of the treatment of patients.

关 键 词：人类免疫缺陷病毒 母婴阻断治疗 治疗依从性 齐多夫定 影响因素 

分 类 号：R512.91[医药卫生—内科学]