慢性主观性耳鸣分类、发生发展机制及治疗新进展  

Classification,pathogenesis,and treatment advances of chronic subjective tinnitus

作　　者：陈倬诣 郑亿庆[1] 杨海弟[1] CHEN Zhuoyi;ZHENG Yiqing;YANG Haidi(Department of Otorhinolaryngology&Head and Neck Surgery,Sun Yat Sen Mem Hospital,Sun Yat Sen University,Guangzhou 510120,Guangdong,China)

机构地区：[1]中山大学孙逸仙纪念医院耳鼻喉头颈外科,广东广州510120

出　　处：《山东大学耳鼻喉眼学报》2023年第4期1-12,共12页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：慢性主观性耳鸣是耳鼻喉科较为常见的症状,其发病率高且临床表现多样,病理机制亦较为复杂。耳鸣的分类和相关神经生理机制研究是指导耳鸣临床诊断和个体化精准医疗的基础。近年来,越来越多的耳鸣研究在上述领域提出了新的思路。新的证据显示,耳鸣的特征维度变化可能比亚型分类更能准确地解释耳鸣的异质性,在临床研究与诊疗方面具有巨大的应用潜力。此外,耳鸣新的网络模型整合了耳鸣本身及其合并症神经生理机制,进一步发展和完善了个体化治疗的理论基础。论文重点总结了耳鸣分类的维度网络模型和耳鸣合并症的三网络模型,并结合最新的指南更新和循证医学证据,对常见的耳鸣治疗方法进行简要概述。Chronic subjective tinnitus characterized by a high incidence rate,diverse clinical manifestations,and a complex pathological mechanism,is a common symptom in otolaryngology.Tinnitus classification and research on its neurophysiological mechanisms serve as a basis for guiding clinical diagnosis and individualized precision medical treatment.In recent years,an increasing number of tinnitus studies have introduced novel concepts in these domains.Emerging evidence shows that dimensional variability of tinnitus characteristics may provide a more accurate understanding of the heterogeneous nature of tinnitus compared to traditional subtype classification,thereby holding significant potential for clinical research and diagnosis applications.In addition,a newly developed tinnitus network model,integrates the neurophysiological mechanisms of tinnitus and its associated complications,further advancing the theoretical basis for individualized tinnitus treatment.This article provides a summary of the dimensional network model for tinnitus classification and the triple network model of tinnitus-associated complications.Additionally,it briefly outlines the common treatment methods for tinnitus incorporating updated guidelines and the latest evidence-based medicine,providing a valuable reference for readers.

关 键 词：慢性主观性耳鸣 分类法 发病机制 脑网络 治疗 

分 类 号：R764.45[医药卫生—耳鼻咽喉科]