中国儿童血管炎诊断与治疗系列专家共识之四——川崎病  

Consensus on diagnosis and treatment of childhood vasculitis in China:Kawasaki disease

作　　者：中国医师协会儿科医师分会风湿免疫学组 樊志丹[2] 俞海国[2] 胡坚[3] 赖建铭[4] Academic Groupof Pediatric Rheumatology and Immunology,Society of Pediatries,Chinese Medical Doctor Association

机构地区：[1]不详 [2]南京医科大学附属儿童医院 [3]天津市儿童医院 [4]首都儿科研究所附属儿童医院

出　　处：《中国实用儿科杂志》2023年第7期481-488,共8页Chinese Journal of Practical Pediatrics

摘　　要：川崎病(KD)是儿童时期较为常见的急性系统性血管炎,全身炎性反应可导致多器官功能损害,出现心血管系统损害、休克综合征和巨噬细胞活化综合征等严重并发症。该共识从风湿免疫角度出发,为不完全KD的早期识别、静脉输注丙种球蛋白治疗时机、补救治疗、重症救治策略、激素与免疫抑制剂的使用及疫苗接种等临床热点问题提出建议,旨在促进临床获得更好的治疗反应和结局。共识基于近年多个国家指南及建议,结合国内诊治的现状和实用性,可为临床医生更好地管理KD提供帮助。Kawasaki disease(KD)is a relatively common acute systemic vasculitis in children.Systemic inflammatory reaction can lead to multiple organ dysfunction,including cardiovascular system damage,KD shock syndrome and macrophage activation syndrome.This expert consensus focuses on clinical management of questions mainly from the perspective of rheumatology and immunology in order to have better treetment outcomes.The questions include diagnostic strategies,prompt treatment of incomplete KD,use of intravenous immunoglobulin(IVIG)with other adjuvant agents for patients with high-risk features of IVIG resistance and/or coronary artery aneurysms,treatment approaches for severe complications and vaccination recommendations.Based on the latest global and national consensus guidelines,combined with China’s actual situation,the consensus present these recommendations to assist physicians in managing KD.

关 键 词：川崎病 血管炎 中国 专家共识 

分 类 号：R72[医药卫生—儿科]