丝氨酸蛋白酶Corin与肾脏疾病的关系研究进展  

Progress of research on the relationship between serine protease corin and kidney disease

作　　者：张艳如 苏晓乐[1] 王利华[1] Zhang Yanru;Su Xiaole;Wang Lihua(Department of Nephrology,Second Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi Province,China)

机构地区：[1]山西医科大学第二医院肾内科,太原030001

出　　处：《中华肾病研究电子杂志》2023年第4期220-223,共4页Chinese Journal of Kidney Disease Investigation（Electronic Edition）

基　　金：国家青年科学基金项目(2F12020028)。

摘　　要：Corin是一种丝氨酸蛋白酶,广泛分布于肾脏上皮组织,可通过活化心房利钠肽而具有利钠、排水、舒张血管等作用。本文综述Corin与高血压、慢性肾脏病等疾病的关系研究进展,以探讨其作为肾脏疾病生物标志物的可能性。Corin is a serine protease widely distributed in the epithelial tissues of the kidney. It can activate atrial natriuretic peptide, having natriuretic, water excretion, and vasodilation effects. This article reviewed the progress of research on the relationship between corin and diseases such as hypertension and chronic kidney disease, in order to explore its potential as a biomarker for kidney disease.

关 键 词：肾脏疾病 丝氨酸蛋白酶 心房利钠肽 诊断 治疗 

分 类 号：R692[医药卫生—泌尿科学]