基于肠道菌群探讨中医药从脾论治慢性便秘  

Traditional Chinese Medicine in the Treatment of Chronic Constipation from Spleen Based on Intestinal Flora

作　　者：陈亚雯 杨军义[2] 毛红[2] CHEN Yawen;YANG Junyi;MAO Hong(Clinical Medical School,Chengdu University of Chinese Medicine,Sichuan Province,Chengdu 610072,China;Department of Proctology,Sichuan Province Second Hospital of Traditional Chinese Medicine,Sichuan Province,Chengdu 610031,China)

机构地区：[1]成都中医药大学临床医学院,四川成都610072 [2]四川省第二中医医院肛肠科,四川成都610031

出　　处：《中国中医药现代远程教育》2023年第17期81-83,共3页Chinese Medicine Modern Distance Education of China

基　　金：四川省中医药管理局第二批四川省名中医毛红工作室建设项目【No.川中医药办函[2022]19号】;国家中医药管理局第七批全国老中医药专家学术经验继承工作项目【No.国中医药办人教函[2021]272号】。

摘　　要：肠道菌群由数量众多的微生物组成,主要寄居于人体肠道之中。越来越多的研究证实,肠道菌群是慢性便秘发病的关键因素之一。中医药对慢性便秘具有显著疗效,这可能是因为中医药对肠道菌群的结构、数量等都具有良好的调节作用。各种单味中药或复方中药、中成药等,通过活性成分,对肠道菌群的结构产生调节,从而改善慢性便秘的病情、进展。此文在肠道菌群的基础上,分析肠道菌群、脾脏及慢性便秘之间的关系,探究对肠道菌群具有良好调整作用的中药,深入研究脾、大肠在中医药理论体系之中的联系,为从脾论治慢性便秘,同时也为慢性便秘的发生、发展、临床防治研究提供理论支持。此文的论述可为慢性便秘的研究和治疗提供新的思路和方法。Intestinal microflora consists of a large number of microorganisms,which mainly inhabit the human intestinal tract.In re-cent years,more and more studies have gradually confirmed that intestinal flora is one of the key factors in the pathogenesis of chronic constipation.Traditional Chinese medicine has a significant effect in the treatment of chronic constipation,which may be due to its good regulatory effect on the structure and quantity of intestinal flora.Various single or compound Chinese medicines,Chinese patent medicines,etc.regulate the structure of intestinal flora through active ingredients,so as to improve the condition and progress of chronic constipation.This article aims to analyze the relationship between intestinal flora,spleen and chronic constipation on the basis of intestinal flora,explore the traditional Chinese medicine that has a good regulatory effect on intestinal flora,and deeply study the re-lationship between spleen and large intestine in the theoretical system of traditional Chinese medicine,so as to provide theoretical sup-port for the treatment of chronic constipation from the spleen,as well as for the occurrence,development,clinical prevention and treat-ment of chronic constipation.The discussion in this paper can provide new ideas and methods for the research and treatment of chronic constipation.

关 键 词：慢性便秘 脾虚证 肠道菌群 中医药疗法 综述 

分 类 号：R256.35[医药卫生—中医内科学]