血府逐瘀汤加味对冠心病经皮冠状动脉介入治疗术后再狭窄气虚血瘀证患者的影响  

Effect of modified Xuefu Zhuyu decoction on patients with Qi deficiency and blood stasis syndrome of restenosis after percutaneous coronary intervention for coronary heart disease

作　　者：张莉想 刘学文 王东[2] ZHANG Lixiang;LIU Xuewen;WANG Dong(Fouth Department of Internal Medicine,Liaoning Fengtian Hospital of Traditional Chinese Medicine,Shenyang,Liaoning,110000,China;Department of Endocrinology,Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang,Liaoning,110033,China)

机构地区：[1]辽宁奉天中医院内四科,辽宁沈阳110000 [2]辽宁中医药大学附属医院内分泌科,辽宁沈阳110033

出　　处：《当代医学》2023年第13期26-29,共4页Contemporary Medicine

摘　　要：目的探讨血府逐瘀汤加味对冠心病经皮冠状动脉介入治疗(PCI)术后再狭窄气虚血瘀证患者的影响。方法选取2019年8月至2020年9月本院收治的92例冠心病PCI术后再狭窄气虚血瘀证患者作为研究对象,按照随机数字表法分为观察组与对照组,每组46例。对照组给予常规西医治疗,观察组在对照组基础上加用血府逐瘀汤加味治疗,比较两组临床疗效、中医证候评分、心功能指标[左室射血分数(LVEF)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)]、血浆黏度。结果观察组治疗总有效率为93.48%,高于对照组的76.09%,差异有统计学意义(P<0.05)。治疗前,两组中医证候评分比较差异无统计学意义;治疗后,两组中医证候评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗前,两组LVEF、LVESD、LVEDD比较差异无统计学意义;治疗后,两组LVESD、LVEDD均短于治疗前,LVEF均高于治疗前,且观察组LVESD、LVEDD均短于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。治疗前,两组血浆黏度比较差异无统计学意义;治疗后,两组血浆黏度均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论血府逐瘀汤加味治疗冠心病PCI术后再狭窄气虚血瘀证患者效果显著,可降低患者症状评分,改善其心功能及血浆黏度,值得临床推广应用。Objective To explore the effect of modified Xuefu Zhuyu decoction on patients with Qi deficiency and blood stasis syndrome of restenosis after percutaneous coronary intervention(PCI)for coronary heart disease.Methods 92 patients with qi deficiency and blood stasis syndrome of coronary heart disease with restenosis after PCI admitted to our hospital from August 2019 to September 2020 were selected as the research subjects,they were divided into observation group and control group according to the random number table method,with 46 cases in each group.The control group was treated with conventional Western Medicine,and the observation group was treated with Xuefu Zhuyu decoction on the basis of the control group,the clinical efficacy,Traditional Chinese Medicine syndrome score,cardiac function indexes(left ventricular ejection fraction[LVEF],left ventricular end systolic diameter[LVESD],left ventricular end diastolic diameter[LVEDD])and plasma viscosity were compared between the two groups.Results The total effective rate in the observation group was 93.48%,which was higher than 76.09%in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in Traditional Chinese Medicine syndrome scores between the two groups;after treatment,the Traditional Chinese Medicine syndrome scores of the two groups were lower than those before treatment,and the observation group was lower than the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in LVEF,LVESD and LVEDD between the two groups;after treatment,the LVESD and LVEDD of the two groups were shorter than those before treatment,and the LVEF was higher than that before treatment,and the LVESD and LVEDD in the observation group were shorter than those in the control group,and the LVEF was higher than that in the control group,the differences were statistically significant(P<0.05).Before treatment,there was no significan

关 键 词：冠心病 经皮冠状动脉介入治疗 气虚血瘀证 血府逐瘀汤加味 

分 类 号：R541.4[医药卫生—心血管疾病]