体外冲击波与内镜手术治疗泌尿系结石的疗效和安全性  

The efficacy and safety of extracorporeal shock wave and endoscopic surgery in the treatment of urinary tract stones

作　　者：曾宪辉[1] 管德辉[1] 张磊[1] 韩建军[1] 刘家炜 ZENG Xianhui;GUAN Dehui;ZHANG Lei;HAN Jianjun;LIU Jiawei(Third Department of Surgery,Armed Police Heilongjiang Corps Hospital,Harbin,Heilongjiang,150076,China)

机构地区：[1]武警黑龙江总队医院外三科,黑龙江哈尔滨150076

出　　处：《当代医学》2023年第17期103-106,共4页Contemporary Medicine

摘　　要：目的探讨体外冲击波与内镜手术治疗泌尿系结石的疗效和安全性。方法选取2019年1月至2020年12月本院收治的100例泌尿系结石患者作为研究对象,按照随机数字表法分为两组,各50例。对照组行体外冲击波治疗,观察组行内镜手术治疗,比较两组临床指标、炎症因子水平、结石清除率与并发症发生率。结果观察组下床活动时间、住院时间均短于对照组,视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。术前,两组肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)水平比较差异无统计学意义;术后,两组TNF-α、hs-CRP、IL-6水平均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组结石清除率为98.00%,高于对照组的84.00%,并发症发生率为4.00%,低于对照组的20.00%,差异有统计学意义(P<0.05)。结论内镜手术治疗泌尿系结石效果确切,可明显提高患者结石清除率,利于患者术后恢复,减轻疼痛程度及炎症反应,降低术后并发症发生率,值得临床推广应用。Objective To explore the efficacy and safety of extracorporeal shock wave and endoscopic surgery in the treatment of urinary tract stones.Methods 100 patients with urinary tract stones admitted to our hospital from January 2019 to December 2020 were selected as the study subjects,and they were divided into the two groups according to the random number table method,with 50 cases in each group.The control group was treated with extracorporeal shock wave,and the observation group was treated with endoscopic surgery,the clinical indicators,levels of inflammatory factors,stone clearance rate and complication rate were compared between the two groups.Results The time of getting out of bed and hospitalization in the observation group were shorter than those in the control group,and the visual analogue scale(VAS)score was lower than that in the control group,the differences were statistically significant(P<0.05).Before operation,there were no significant differences in the levels of tumor necrosis factor-α(TNF-α),hypersensitive C-reactive protein(hs-CRP)and interleukin-6(IL-6)between the two groups;after operation,the levels of TNF-α,hs-CRP and IL-6 of the two groups were lower than those before operation,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).The stone clearance rate in the observation group was 98.00%,which was higher than 84.00%in the control group,and the complication rate was 4.00%,which was lower than 20.00%in the control group,the differences were statistically significant(P<0.05).Conclusion Endoscopic surgery has definite effect in the treatment of urinary tract stones,which can significantly improve the stone clearance rate of patients,facilitate postoperative recovery,reduce pain and inflammatory reactions,and reduce the incidence of postoperative complications,it is worthy of clinical promotion and application.

关 键 词：泌尿系结石 体外冲击波 内镜手术 

分 类 号：R691.4[医药卫生—泌尿科学]