奥马珠单抗治疗阿司匹林哮喘合并中耳炎和鼻窦炎一例  

Omalizumab Treats Aspirin-Induced Asthma Complicated With Nasosinusitis and Otitis Media:Report of One Case

作　　者：汤蕊 雷曙槟 王轶 TANG Rui;LEI Shubin;WANG Yi(Department of Allergy,Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease,National Clinical Research Center for Dermatologic and Immunologic Diseases,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Eight-Year Program of Clinical Medicine,CAMS and PUMC,Beijing 100730,China;Department of Otolaryngology and Head and Neck Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院、北京协和医学院、北京协和医院变态(过敏)反应科、过敏性疾病精准诊疗研究北京市重点实验室、国家皮肤与免疫疾病临床医学研究中心,北京100730 [2]中国医学科学院、北京协和医学院八年制临床医学,北京100730 [3]中国医学科学院、北京协和医学院、北京协和医院耳鼻喉头颈外科,北京100730

出　　处：《中国医学科学院学报》2023年第4期699-702,共4页Acta Academiae Medicinae Sinicae

摘　　要：奥马珠单抗是一种重组人源化单克隆抗体,为抗IgE靶向生物制剂,是全球首个获批治疗中至重度支气管哮喘的靶向治疗药物。本文对1例阿司匹林哮喘伴分泌性中耳炎及鼻窦炎患者进行回顾性分析,探讨奥马珠单抗在治疗哮喘及其合并症中的价值,为临床实践提供依据。Omalizumab,as a biological agent targeting IgE,is a recombinant humanized monoclonal antibody and the first targeted drug approved for treating moderate-to-severe bronchial asthma.By reviewing one case of aspirin-induced asthma complicated with nasosinusitis and otitis media,we discussed the value of omalizumab in the treatment of asthma and its complications,aiming to provide a reference for clinical practice.

关 键 词：奥马珠单抗 哮喘 鼻窦炎 中耳炎 

分 类 号：R593.1[医药卫生—内科学]