内镜下高频电凝电切术治疗结肠息肉患者的临床疗效及对患者肠道菌群的影响  

Clinical efficacy and impact on gut microbiota of endoscopic high-frequency electrocoagulation and electrocautery for the treatment of colon polyps in patients

作　　者：刘頔 LIU Di(Endoscopy Center of Fuxin Central Hospital,Fuxin,Liaoning,123000,China)

机构地区：[1]阜新市中心医院内镜中心,辽宁阜新123000

出　　处：《当代医学》2023年第7期118-120,共3页Contemporary Medicine

摘　　要：目的探讨内镜下高频电凝电切术治疗结肠息肉的临床疗效及对患者肠道菌群的影响。方法选取2018年10月至2020年10月本院收治82例结肠息肉患者作为研究对象,按照随机数字表法分为对照组与观察组,各41例。对照组行传统手术治疗,观察组行内镜下高频电凝电切术治疗。比较两组手术相关指标、肠道菌群变化和并发症发生情况。结果观察组术中出血量少于对照组,卧床时间短于对照组,差异有统计学意义(P<0.05);术前,两组大肠埃希菌、乳酸杆菌、双歧杆菌肠道菌群比较差异无统计学意义;术后,两组大肠埃希菌低于术前,乳酸杆菌、双歧杆菌均高于术前,且观察组大肠埃希菌低于对照组,乳酸杆菌、双歧杆菌均高于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为4.88%,低于对照组的19.51%,差异有统计学意义(P<0.05)。结论内镜下高频电凝电切术治疗结肠息肉疗效显著,可改善患者肠道菌群,减轻机体损伤,缩短卧床时间,安全性高,值得临床推广应用。Objective To explore the clinical efficacy and impact on gut microbiota of endoscopic high-frequency electrocoagulation and electrocautery for the treatment of colon polyps in patients.Methods 82 patients with colon polyps admitted to our hospital from October 2018 to October 2020 were selected as the study subjects,and they were randomly divided into control group and observation group according to random number table method,with 41 cases in each group.The control group received traditional surgical treatment,while the observation group received endoscopic high-frequency electrocoagulation and electrocautery.The surgical related indicators,changes in gut microbiota and complications were compared between the two groups.Results The intraoperative bleeding in the observation group was less than that in the control group,and the bedtime was shorter than that in the control group,the difference was statistically significant(P<0.05).Before surgery,there was no significant difference in intestinal flora of Escherichia coli,Lactobacillus and bifidobacterium between the two groups;after surgery,the postoperative levels of Escherichia coli in two groups were lower than those before surgery,while lactobacilli and bifidobacteria were higher than those before surgery,and the postoperative levels of Escherichia coli in the observation group were lower than those in the control group,while lactobacilli and bifidobacteria were higher than those in the control group,the difference was statistically significant(P<0.05).The incidence of complications in the observation group was 4.88%,which was lower than 19.51%in the control group,the difference was statistically significant(P<0.05).Conclusion Endoscopic high-frequency electrocoagulation and electrocautery has significant efficacy in the treatment of colon polyps,which can improve the intestinal flora of patients,reduce body damage,shorten the bed time,and have high safety,it is worthy of clinical promotion and application.

关 键 词：结肠息肉 内镜下高频电凝电刀术 肠道菌群 出血量 并发症 

分 类 号：R656.9[医药卫生—外科学]