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作 者:艾尔肯·买买提 张晓峰[1] 齐保韦 AErken MAIMAIMAT;ZHANG Xiaofeng;QI Baowei(Department of Emergency Medicine,the First People's Hospital of Aksu Prefecture,Aksu,Xinjiang,843000,China)
机构地区:[1]阿克苏地区第一人民医院急诊内科,新疆阿克苏843000
出 处:《当代医学》2023年第2期62-64,共3页Contemporary Medicine
摘 要:目的分析纤维支气管镜治疗急危重症合并严重肺部感染的疗效及可行性。方法选取2020年1—12月本院收治的76例急危重症合并严重肺部感染患者作为研究对象,按照随机数字表法分为对照组(n=37)与观察组(n=39)。对照组采用常规治疗,观察组在对照组基础上联合纤维支气管镜治疗,比较两组临床症状消失时间、住院时间、炎症因子水平、临床疗效。结果观察组痰液减少时间、肺啰音消失时间、退热时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。治疗前,两组白细胞介素-6(IL-6)、C反应蛋白(CRP)水平比较差异无统计学意义;治疗后,两组IL-6、CRP水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为94.87%,高于对照组的70.27%,差异有统计学意义(P<0.05)。结论常规治疗联合纤维支气管镜治疗急危重症合并严重肺部感染效果确切,能有效缓解患者临床症状,降低炎症因子水平,促进患者恢复,缩短住院时间,值得临床推广应用。Objective To analyze the efficacy and feasibility of fiberoptic bronchoscopy in the treatment of acute and severe pulmonary infection.Methods A total of 76 patients with acute and severe pulmonary infection admitted to our hospital from January to December 2020 were selected as the study subjects,and they were divided into control group(n=37)and observation group(n=39)according to the random number table method.The control group was treated with routine treatment,and the observation group was treated with fiberoptic bronchoscopy on the basis of the control group,the disappearance time of clinical symptoms,hospitalization time,inflammatory factor level and clinical efficacy were compared between the two groups.Results The sputum reduction time,lung rale disappearance time,antipyretic time and hospitalization time in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in interleukin-6(IL-6),Creaction protein(CRP)levels between the two groups;after treatment,the levels of IL-6 and CRP in the two groups were lower than those before treatment,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 94.87%,which was higher than 70.27%in the control group,and the difference was statistically significant(P<0.05).Conclusion On the basis of conventional treatment combined with fiberoptic bronchoscopy is effective in the treatment of acute and severe pulmonary infection,it can effectively alleviate the clinical symptoms of patients,reduce the level of inflammatory factors,promote recovery and shorten the hospitalization time,it is worthy of clinical application.
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