伊伐布雷定治疗快速性心律失常的效果及对患者康复率的影响  

Effect of ivabradine in the treatment of tachyarrhythmia and its influence on the recovery rate of patients

作　　者：陈忠锐 CHEN Zhongrui(Department of Cardiology,Benxi Central Hospital,Benxi,Liaoning,117000,China)

机构地区：[1]本溪市中心医院心内科,辽宁本溪117000

出　　处：《当代医学》2023年第2期80-82,共3页Contemporary Medicine

摘　　要：目的探究伊伐布雷定治疗快速性心律失常的效果及对患者康复率的影响。方法选取2018年5月至2020年5月本院收治的200例快速性心律失常患者作为研究对象,按照随机数字表法分为对照组与观察组,各100例。对照组给予美托洛尔治疗,观察组给予伊伐布雷定治疗,比较两组收缩压、舒张压、心率、症状恢复情况、康复率、不良反应发生率。结果治疗后,观察组收缩压[(105.11±13.25)mmHg]、舒张压[(73.02±9.85)mmHg]和心率[(85.63±15.25)次/min]均低于对照组[(113.32±15.63)mmHg、(82.45±9.89)mmHg、(96.56±14.42)次/min],差异有统计学意义(P<0.05)。治疗后,观察组睡眠不安率(2.00%)、心前区不适率(5.00%)、心悸率(4.00%)和胸闷率(4.00%)均低于对照组(13.00%、13.00%、17.00%、16.00%),差异有统计学意义(P<0.05)。观察组康复率(98.00%)高于对照组(88.00%),差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论伊伐布雷定治疗快速性心律失常效果显著,可明显提升患者康复率,促进症状恢复,值得临床推广应用。Objective To explore the effect of ivabradine in the treatment of tachyarrhythmia and its influence on the recovery rate of patients.Methods A total of 200 patients with tachyarrhythmia admitted to our hospital from May 2018 to May 2020 were selected as the research subjects and they were divided into control group and observation group according to random number table method,with 100 cases in each group.The control group was treated with metoprolol and the observation group was treated with ivabradine,the systolic blood pressure,diastolic blood pressure,heart rate,symptom recovery,recovery rate and incidence of adverse reactions were compared between the two groups.Results After treatment,systolic blood pressure([105.11±13.25]mmHg),diastolic blood pressure([73.02±9.85]mmHg)and heart rate([85.63±15.25]times/min)in the observation group were lower than those in the control group([113.32±15.63]mmHg,[82.45±9.89]mmHg,[96.56±14.42]times/min),the differences were statistically significant(P<0.05).After treatment,the sleep restlessness rate(2.00%),precardiac discomfort rate(5.00%),palpitation rate(4.00%)and chest tightness rate(4.00%)in the observation group were lower than those in the control group(13.00%,13.00%,17.00%,16.00%),and the differences were statistically significant(P<0.05).The recovery rate of observation group(98.00%)was higher than that of control group(88.00%),and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion Ivabradine has significant effect on tachyarrhythmia,which can improve the recovery rate of patients and promote the recovery of symptoms,it is worthy of clinical application.

关 键 词：伊伐布雷定 快速性心律失常 康复率 不良反应 

分 类 号：R541.7[医药卫生—心血管疾病]