纵隔子宫体外受精/卵泡浆内单精子注射-胚胎移植助孕前行宫腔镜下子宫纵隔切除术对患者妊娠结局的影响  

The effect of hysteroscopic mediastinal resection before in vitro fertilization/intrafollicular sperm injectionembryo transfer of mediastinal uterus on pregnancy outcome

作　　者：孙天辰 姜晓君 倪娜 任洁 SUN Tianchen;JIANG Xiaojun;NI Na;REN Jie(Department of Obstetrics and Gynecology,Shenyang 204 Hospital,Shenyang,Liaoning,110043,China)

机构地区：[1]沈阳二〇四医院妇产科,辽宁沈阳110043

出　　处：《当代医学》2023年第3期152-154,共3页Contemporary Medicine

摘　　要：目的探讨纵隔子宫体外受精/卵泡浆内单精子注射-胚胎移植(IVF/ICSI-ET)助孕前行宫腔镜下子宫纵隔切除术对患者妊娠结局的影响。方法选取2016年1月至2019年12月本院收治的68例患有子宫纵隔且同意行IVE/ICSI-ET助孕者作为研究对象,根据是否开展宫腔镜下子宫纵隔切除术分为未手术组(n=29)与手术组(n=39),另选取同期74例宫腔镜检查发现子宫形态正常但行IVE/ICSI-ET助孕者作为对照组,比较3组妊娠结局。结果3组流产率、足月分娩率比较差异无统计学意义;手术组、对照组早产率均低于未手术组,差异有统计学意义(P<0.05);手术组、对照组早产率比较差异无统计学意义。结论经宫腔镜下子宫纵隔切除术治疗后,对患有纵隔子宫的患者开展IVE/ICSI-ET助孕,能有效减少早产情况的发生,且不影响妊娠结局,与子宫形态正常者妊娠率、分娩率无明显差异。Objective To investigate the effect of hysteroscopic mediastinal resection before in vitro fertilization/intrafollicular sperm injectionembryo transfer(IVF/ICSI-ET)of mediastinal uterus on pregnancy outcome.Methods 68 patients with uterine mediastinum admitted to our hospital from January 2016 to December 2019 who agreed to receive IVE/ICSI-ET assisted pregnancy were selected as the research subjects,and they were divided into the non-operation group(n=29)and the operation group(n=39)according to whether hysteroscopic mediastinal resection was performed,74 patients with normal uterus morphology found by hysteroscopy during the same period but received IVE/ICSI-ET assisted pregnancy were selected as the control group,and the pregnancy outcome were compared among the three groups.Results There was no significant difference in abortion rate and term birth rate among the three groups;the premature delivery rate in the operation group and the control group was lower than that in the non-operation group,and the differences were statistically significant(P<0.05);there was no significant difference in preterm birth rate between the operation group and the control group.Conclusion After hysteroscopic hysterectomy,IVE/ICSI-ET assisted pregnancy for patients with mediastinal uterus can effectively reduce the occurrence of premature delivery without affecting the pregnancy outcome,there is no significant difference between the pregnancy rate and the delivery rate of those with normal uterine morphology.

关 键 词：宫腔镜子宫纵隔切除术 体外受精/卵泡浆内单精子注射-胚胎移植助孕 纵隔子宫 

分 类 号：R714.8[医药卫生—妇产科学]