2021-2022年河南省高危异性性行为HIV暴露后预防人群的行为特征  

Behavioral characteristics of high-risk heterosexual HIV-exposed people in Henan province from 2021 to 2022

作　　者：王奇[1] 徐亚珂 李艾嘉 崔艳 张玮钰 施建春 朱新朋[1] 张国龙 WANG Qi;XU Yake;LI Aijia;CUI Yan;ZHANG Weiyu;SHI Jianchun;ZHU Xinpeng;ZHANG Guolong(Institute of STD AIDS Prevention and Control,Henan Center for Disease Control and Prevention,Zhengzhou,Henan 450016,China;Department of Clinical Medicine,Medical college of Zhengzhou University)

机构地区：[1]河南省疾病预防控制中心性病艾滋病防治研究所,河南郑州450016 [2]郑州大学医学院临床医学系

出　　处：《现代疾病预防控制》2023年第8期561-564,599,共5页MODERN DISEASE CONTROL AND PREVENTION

基　　金：河南省科技厅项目(202102310461)。

摘　　要：目的 了解河南省部分地区高危异性性行为后接受HIV暴露后预防(PEP)人群的特征及预防情况,分析影响及时预防的有关因素。方法 对2021-2022年在河南省11个地市和2个县(区)的14家开展PEP服务的门诊就诊的高危异性性行为后接受PEP者进行面对面调查,收集其一般人口学、高危性行为及接受PEP服务的相关信息,采用非条件logistic回归模型分析影响预防及时的因素。结果 共有560例高危异性PEP人群纳入调查,其中以已婚(43.92%)、男性(90.18%)、大专及以上(65.89%)、干部或职员(44.46%)为主,通过酒吧等场所线下获取临时性伴占49.64%(278人),全程使用安全套的比例仅为11.78%(66人),24 h时内及时获取到药物预防服务的比例为66.43%(372人)。多因素分析结果显示,接受PEP服务人群中,性伴未进行HIV检测的不及时预防风险是性伴进行了HIV检测者的2.89倍(OR=2.89,95%CI:1.76~5.01),高危性行为发生在居住地的不及时预防风险降低(OR=0.75,95%CI:0.60~0.94),知晓PEP知识的不及时预防风险降低(OR=0.25,95%CI:0.15~0.42)。结论 高危异性PEP人群中无保护性行为、性伴HIV感染情况未知的比例均较高;加强PEP宣传及PEP门诊建设,可有效提高高危异性性行为人群获取PEP服务的及时性。Objective To understand the behavioral characteristics and PEP status of people having high-risk heterosexual behavior in some areas of Henan province,and analyze the relevant influencing factors of timely prophylaxis.Methods A face-toface interviewing survey was carried out in people who received post-exposure prophylaxis(PEP)in the 14 PEP clinics distributing in 11 cities and 2 counties of Henan from 2021-2022 to collect the general demographic characteristics,high-risk sex behavior,and information relevant to PEP;the relevant factors influencing the timely prophylaxis were analyzed using unconditional logistic regression.Results A total of 560 people who received PEP after having high-risk heterosexual behavior were recruited for the survey.Of them,43.92%were married;90.18%were male;65.89%had education level of college or above;cadres or clerks accounted for 44.46%.The exposed people obtaining temporary sexual partners in bars and other entertainment places accounted for 49.64%(278 people);the proportion of exposed people with condom used throughout the entire sex duration was only 11.78%.Of the exposed people,66.43%(372 people)obtained PEP treatment within 24h.The multivariate analysis results showed that the risk of untimely prophylaxis for those whose sex partners had not undergone HIV testing was 2.89 times higher than those whose sex partners had undergone HIV test(OR=2.89,95%CI:1.76-5.01);the risk of untimely prophylaxis for the people who had the high-risk sexual behavior occurring in the residential area was lower(OR=0.75,95%CI:0.60-0.94);the risk of untimely prophylaxis for those knowing PEP was lower(OR=0.25,95%CI:0.15-0.42).Conclusions The proportion of unprotected sexual behavior and unknown HIV infection status of sexual partners among the people accepting PEP were high.Strengthening the publicity of PEP and encouraging cities to set up PEP clinics can effectively improve the timeliness of PEP.

关 键 词：艾滋病 高危异性性行为 HIV暴露后预防 影响因素 

分 类 号：R512.91[医药卫生—内科学]