2013-2021年杭州市糖尿病死亡及疾病负担分析  

Mortality and disease burden of diabetes in Hangzhou City from 2013 to 2021

作　　者：张铁威 张艳[1] 刘冰[1] 秦康 李标 徐珏[1] ZHANG Tiewei;ZHANG Yan;LIU Bing;QIN Kang;LI Biao;XU Jue(Department of Non-communicable Diseases Control and Prevention,Hangzhou Center for Disease Control and Prevention,Hangzhou,Zhejiang 310021,China)

机构地区：[1]杭州市疾病预防控制中心慢性非传染性疾病防制所,浙江杭州310021

出　　处：《预防医学》2023年第9期752-756,共5页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：杭州市卫生科技计划一般项目(A20230192);杭州市农业与社会发展一般项目(20201203B207)。

摘　　要：目的了解2013—2021年杭州市糖尿病死亡率及疾病负担,为完善糖尿病防控策略提供参考。方法通过杭州市疾病预防控制中心慢性病及死因监测系统收集2013—2021年杭州市糖尿病发病和死亡资料,计算粗死亡率和标化死亡率;收集中国成人慢性病及其危险因素监测(CCDRFS)项目的糖尿病患病率资料,参照全球疾病负担研究的方法计算早死损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY),评价疾病负担;计算平均年度变化百分比(AAPC)评价糖尿病死亡率及疾病负担的变化趋势。结果2013—2021年杭州市糖尿病死亡8686例,年均粗死亡率为13.17/10万,标化死亡率为10.89/10万;粗死亡率呈上升趋势(AAPC=2.62%,P<0.05),标化死亡率未见明显趋势(P>0.05)。女性糖尿病粗死亡率和标化死亡率分别为14.11/10万和12.16/10万,高于男性的12.21/10万和9.71/10万(均P<0.05);但男性粗死亡率上升较快(男性AAPC=4.46%,P<0.05;女性AAPC=1.09%,P>0.05)。2013—2021年杭州市糖尿病YLL、YLD和DALY分别为155.42千人年、1246.73千人年和1402.15千人年,YLL率、YLD率和DALY率分别为2.36人年/千人、18.90人年/千人和21.25人年/千人,均呈上升趋势(AAPC=1.57%、6.03%和7.11%,均P<0.05)。男性糖尿病DALY率高于女性(P<0.05),且上升速度高于女性(男性AAPC=8.37%,女性AAPC=5.54%,均P<0.05)。结论2013—2021年杭州市糖尿病死亡率处于较高水平,疾病负担特别是伤残负担快速增长,其中男性糖尿病疾病负担更为严重。Objective To investigate the mortality and disease burden of diabetes in Hangzhou City from 2013 to 2021,so as to provide insights into improving diabetes prevention and control strategies.Methods Data on morbidity and mortality of diabetes in Hangzhou City from 2013 to 2021 were collected through the Chronic Disease and Death Cause Monitoring System of Hangzhou Center for Disease Control and Prevention,and the crude and age-standardized mortali⁃ty(standardized by the population of the Seventh National Population Census in China in 2020)were calculated.Data on the prevalence of diabetes were collected from the China Chronic Disease and Risk Factors Surveillance(CCDRFS),and the burden of disease was evaluated by calculating years of life lost(YLL),years lived with disability(YLD)and disability-adjusted years(DALY)with reference to the methodology of the Global Burden of Disease Study(GBD).The trends in mortality and disease burden of diabetes were evaluated with the average annual percent change(AAPC).Re⁃sults There were 8686 deaths of diabetes in Hangzhou City from 2013 to 2021,with the average annual crude mortal⁃ity of 13.17/105 and age-standardized mortality of 10.89/105.The crude mortality of diabetes showed a tendency towards a rise(AAPC=2.62%,P<0.05),while the trend in age-standardized mortality was not significant(P>0.05).The crude and age-standardized mortality of diabetes were higher in women than in men(14.11/105 vs.12.21/105,12.16/105 vs.9.71/105;both P<0.05);however,the crude mortality in men increased more rapidly(men:AAPC=4.46%,P<0.05;wom⁃en:AAPC=1.09%,P>0.05).The YLL,YLD and DALY of diabetes were 155.42,1246.73 and 1402.15 thousand per⁃son-years,and the rates of YLL,YLD and DALY were 2.36,18.90 and 21.25 person-years per thousand,respectively.The rates of YLL,YLD and DALY appeared a tendency towards a rise(AAPC=1.57%,6.03%and 7.11%,all P<0.05).Higher rates of DALY and more remarkable increase were seen in men than in women(P<0.05;AAPC=8.37%,5.54%,both P<0.05).Conclusions The mortality of

关 键 词：糖尿病 死亡率 疾病负担 伤残调整寿命年 

分 类 号：R587.1[医药卫生—内分泌]