奇神经节脉冲射频对慢性骨盆疼痛综合征的疗效观察  

Efficacy of ganglion impar pulsed radiofrequency on chronic pelvic pain syndrome

作　　者：任耀强 田全发 贺建熊 李泰峰 REN Yaoqiang;TIAN Quanfa;HE Jianxiong;LI Taifeng(Department of Urological Surgery,Shanxi Fenyang Hospital,Lyuliang,Shanxi 032200,China;Department of Pain,Shanxi Fenyang Hospital,Lyuliang,Shanxi 032200,China)

机构地区：[1]山西省汾阳医院泌尿外科,山西吕梁032200 [2]山西省汾阳医院疼痛科,山西吕梁032200

出　　处：《安徽医药》2023年第9期1845-1848,共4页Anhui Medical and Pharmaceutical Journal

基　　金：吕梁市卫生健康委员会重点研发项目(2020SHFZ75)。

摘　　要：目的探讨奇神经节脉冲射频治疗慢性骨盆疼痛综合征(CPPS)的疗效。方法选取2020年10月至2021年10月于山西省汾阳医院就诊的CPPS病人78例,均为男性,按随机数字表法分为对照组(39例)和研究组(39例)。对照组给予盐酸坦索罗辛缓释胶囊治疗,研究组给予奇神经脉冲射频治疗,观察两组病人炎性因子水平,骨盆疼痛情况,临床疗效及并发症发生情况。结果治疗前研究组与对照组炎性因子水平差异无统计学意义,治疗后研究组肿瘤坏死因子-α(TNF-α)(34.20±7.32)ng/L、白细胞介素(IL)-8(27.15±6.48)ng/L、IL-10(21.28±4.56)ng/L水平均明显低于对照组TNF-α(57.69±7.55)ng/L、IL-8(34.19±6.63)ng/L、IL-10(36.22±4.31)ng/L(P<0.05)。治疗前研究组与对照组视觉模拟评分法(VAS)评分、慢性前列腺炎症状指数(NIH-CPSI)水平差异无统计学意义,治疗后研究组VAS评分(2.11±0.49)分,NIH-CPSI(3.22±4.02)分,均低于对照组VAS评分(3.29±0.52)分,NIH-CPSI(6.67±4.31)分。研究组治疗总有效率[97.44%(38/39)]高于对照组[84.62%(33/39)](P<0.05);两组并发症总发生率比较,差异无统计学意义(P>0.05)。结论奇神经节脉冲射频治疗CPPS病人,能够改善病人炎性反应和骨盆疼痛情况,且疗效较好,安全性较佳。Objective To investigate the efficacy of ganglion impar pulsed radiofrequency in the treatment of chronic pelvic pain syndrome(CPPS).Methods A total of 78 male patients with CPPS who were treated in Fenyang Hospital of Shanxi Province from October 2020 to October 2021 were selected and assigned into the control group(n=39)and the study group(n=39)according to the random number table method.The control group was treated with tamsulosin hydrochloride sustained-release capsules,and the study group was treated with ganglion impar pulsed radiofrequency.The levels of inflammatory factors,pelvic pain,clinical efficacy and complications were observed in the two groups.Results There was no significant difference in the levels of inflammatory factors between the study group and the control group before treatment.After treatment,the levels of tumor necrosis factor-α(TNF-α),interleukin-8(IL8)and interleukin-10(IL-10)in the study group were significantly lower than those in the control group[(34.20±7.32)ng/L vs.(57.69±7.55)ng/L,(27.15±6.48)ng/L vs.(34.19±6.63)ng/L,(21.28±4.56)ng/L vs.(36.22±4.31)ng/L](P<0.05).Before treatment,there were no significant differences in visual analogue scale(VAS)score and chronic prostatitis symptom index(NIH-CPSI)level between the study group and the control group.After treatment,the VAS score and NIH-CPSI of the study group were lower than those of the control group[(2.11±0.49)vs.(3.29±0.52),(3.22±4.02)vs.(6.67±4.31)](P<0.05).The total effective rate of treatment in the study group was higher than that in the control group[97.44%(38/39)vs.84.62%(33/39)](P<0.05).No significant difference in the total incidence of complications was found between the two groups(P>0.05).Conclusion Ganglion impar pulsed radiofrequency for the treatment of CPPS patients can improve the inflammatory response and pelvic pain,with better curative effect and safety.

关 键 词：慢性盆腔疼痛综合征 奇神经节脉冲射频 疗效 前列腺液 肿瘤坏死因子-α 白细胞介素-8 白细胞介素-10 

分 类 号：R697.33[医药卫生—泌尿科学]