血清胆红素、糖化血红蛋白和血脂在2型糖尿病合并冠心病中的应用价值  

Application Value of Serum Bilirubin,Glycosylated Hemoglobin and Blood Lipid in Type 2 Diabetes Complicated with Coronary Heart Disease

作　　者：曹会 陈少 周丽 CAO Hui;CHEN Shao;ZHOU Li(Department of Laboratory Medicine,Siyang Kangda Hospital,Suqian,Jiangsu Province,223700 China)

机构地区：[1]泗阳康达医院检验科,江苏宿迁223700

出　　处：《糖尿病新世界》2023年第13期58-60,64,共4页Diabetes New World Magazine

摘　　要：目的 分析血清胆红素,糖化血红蛋白和血脂在2型糖尿病合并冠状动脉粥样硬化性心脏病(简称冠心病)中的应用价值。方法 选取2020年8月-2022年10月期间泗阳康达医院诊治的39例2型糖尿病合并冠心病患者作为观察组,同期收集本院接收的38例2型糖尿病未合并冠心病患者作为对照组,所有对象均接受血清胆红素、糖化血红蛋白、血脂检测,对比两组检测结果。结果 观察组血清总胆红素、高密度脂蛋白胆固醇水平均低于对照组,糖化血红蛋白、三酰甘油、总胆固醇、低密度脂蛋白胆固醇水平均高于对照组,差异有统计学意义(P<0.05)。Gensini评分越高的患者血清总胆红素和高密度脂蛋白胆固醇水平越低,糖化血红蛋白、三酰甘油、总胆固醇、低密度脂蛋白胆固醇水平则呈上升趋势,差异有统计学意义(P<0.05)。结论 2型糖尿病合并冠心病患者在临床诊断时,可以通过观察患者血清胆红素、糖化血红蛋白和血脂水平对患者病情进行判断,同时,通过以上指标,还能判断出患者冠状动脉病变程度,为患者病情治疗提供更多可以参考的依据。Objective To analyze the application value of serum bilirubin,Glycated hemoglobin and blood lipids in type 2 diabetes patients with coronary Atherosclerosis heart disease(CHD).Methods From August 2020 to October 2022,39 cases of type 2 diabetes patients with coronary heart disease diagnosed and treated by Siyang Kangda Hospital were selected as the observation group,and 38 cases of type 2 diabetes patients without coronary heart disease received by our hospital were collected at the same time as the control group.All subjects received serum bilirubin,Glycated hemoglobin,and blood lipid tests,and the test results of the two groups were compared.Results The levels of TBil and HDL-C in the observation group were lower than those in the control group,while the levels of HbA1c,TG,TC,and LDL-C were higher than those in the control group,the difference was statistically significant(P<0.05).The higher the Gensini score,the lower the TBil and HDL-C levels in patients,while the HbA1c,TG,TC,and LDL-C levels showed an upward trend,the difference was statistically significant(P<0.05).Conclusion Type 2 diabetes patients with coronary heart disease can be judged by observing the serum bilirubin,glycosylated hemoglobin and blood lipid levels during clinical diagnosis.At the same time,through the above indicators,the degree of coronary artery disease of the patient can also be judged,and more references can be provided for the treatment of the patient's condition.

关 键 词：血清胆红素 糖化血红蛋白 血脂 2型糖尿病 冠心病 

分 类 号：R4[医药卫生—临床医学]