1例尿毒症伴原发性肺淋巴瘤合并脓毒症患者的抗感染治疗分析与药学监护  

Analysis of anti-infective therapy and pharmaceutical care for a patient withuremia and primary pulmonary lymphoma complicated with sepsis

作　　者：孟凡堰[1] 刘江 刘辉 张灵 胡杰 梁紫薇 Fan-Yan MENG;Jiang LIU;Hui LIU;Ling ZHANG;Jie HU;Zi-Wei LIANG(Department of Pharmacy,People's Hospital of Anshun City,Anshun 561000,Guizhou Province,China;Department of Rheumatology and Immunology,People's Hospital of Anshun City,Anshun 561000,Guizhou Province,China)

机构地区：[1]安顺市人民医院药剂科,贵州安顺561000 [2]安顺市人民医院肾内/风湿免疫科,贵州安顺561000

出　　处：《药物流行病学杂志》2023年第7期830-835,共6页Chinese Journal of Pharmacoepidemiology

基　　金：安顺市科技计划项目(安市科社[2021]55号)。

摘　　要：临床药师参与1例尿毒症伴原发性肺淋巴瘤合并脓毒症患者的治疗,结合血液透析、残余肾功能、感染严重程度、抗菌药物的药动学/药效学、影像学与感染指标动态变化、文献资料等,制定了详细的个体化抗感染治疗方案,包括抗菌药物的选择、给药方案的优化等,使患者的感染得到有效控制。同时,通过实施药学监护,无明显不良反应发生,残余肾功能得到充分保护,患者得到安全有效的药物治疗,体现了临床药师的专业价值。The clinical pharmacist participated in the treatment of a patient with uremia and primary pulmonary lymphoma complicated with sepsis,and developed a detailed individualized anti-infective treatment plan,including the selection of antibacterial drugs,the optimization of drug administration plan,etc.,in combination with hemodialysis,residual renal function,the severity of infection,the pharmacokinetic/pharmacodynamic of antibacterial drugs,the dynamic changes of imaging and infection indicators,and literature.Finally,the patient©s infection was effectively controlled,and good therapeutic effect was achieved.At the same time,through the implementation of pharmaceutical care,no adverse drug reactions occurred,residual renal function was fully protected,the patient received safe and effective drug treatment,and the professional value of clinical pharmacists was reflected.

关 键 词：脓毒症 尿毒症 肺淋巴瘤 抗感染治疗 药学监护 

分 类 号：R459.7[医药卫生—急诊医学] R692.5[医药卫生—治疗学] R734.2[医药卫生—临床医学]