高频超声对肝硬化及相关疾病的诊断价值观察  

Diagnostic Value of High Frequency Ultrasound in Liver Cirrhosis and Related Diseases

作　　者：林碧锋 吴明双[2] LIN Bi-feng;WU Ming-shuang(Department of Ultrasound,Putian First Hospital,Fujian Province,Fujian Putian 351100;Department of Ultrasound,Suzhou Jiulong Hospital,Shanghai Jiaotong University School of Medicine,Jiangsu Suzhou 215021)

机构地区：[1]福建省莆田市第一医院超声科,福建莆田351100 [2]上海交通大学医学院附属苏州九龙医院超声科,江苏苏州215021

出　　处：《中国医疗器械信息》2023年第16期118-120,共3页China Medical Device Information

摘　　要：目的:探究高频超声在肝硬化及相关疾病中的诊断价值。方法:选择2015年6月~2020年5月收治的109例肝硬化患者,所有患者均行常规腹部低频超声及高频超声检查。以穿刺活检结果作为诊断判别的“金标准”,进一步对高频超声或者常规腹部低频超声应用于肝硬化及相关疾病的实际诊断结果做对比分析,另分析高频及常规腹部低频超声与穿刺活检结果的一致性。结果:109例患者经穿刺活检共发现肝被膜下结节77例,包括再生结节31例,肝细胞肝癌28例,血管瘤18例;高频超声诊断在再生结节、血管瘤、肝细胞癌等肝硬化及相关疾病中的检出率为87.10%,94.44%、96.43%,均高于常规超声检查的45.16%、44.44%、60.71%,差异有统计学意义(P<0.05);高频超声在肝硬化及相关疾病诊断中灵敏度、准确度为89.29%、95.41%,均高于常规超声检查的46.43%、82.57%,差异显著,且具有统计学意义(P<0.05);两种不同检查手段的特异度对比差异小,且无统计学意义(P>0.05)。Kappa检验结果为:高频超声与穿刺活检结果的一致性良好(Kappa值=0.878,P=0.000);常规超声与穿刺活检结果的一致性尚可(Kappa值=0.476,P=0.000)。结论:高频超声在肝硬化及相关疾病诊断中具有较高的应用价值,能够补充常规腹部低频超声的不足,可直观分析肝硬化患者门脉系统血流变化,可实现对患者病情程度的准确评估,并可为其鉴别和诊断提供重要的参考依据。Objective:To explore the diagnostic value of high-frequency ultrasound in liver cirrhosis and related diseases.Methods:109 patients with cirrhosis admitted to our hospital from June 2015 to May 2020 were selected.All patients underwent routine abdominal low-frequency ultrasound and high-frequency ultrasound.The results of puncture biopsy were used as the“gold standard”to analyze the diagnostic results of high-frequency ultrasound and conventional low-frequency abdominal ultrasound in liver cirrhosis and related diseases,and the consistency between high-frequency ultrasound and conventional low-frequency abdominal ultrasound and puncture biopsy results was also analyzed.Results:77 cases of subcapsular nodules were found,including 31 cases of regenerated nodules,28 cases of hepatocellular carcinoma and 18 cases of hemangioma.The detection rates of high frequency ultrasound in regenerated nodules,hemangioma,hepatocellular carcinoma and other liver cirrhosis and related diseases were 87.10%,94.44%,96.43%,which were higher than 45.16%,44.44%,60.71%of conventional ultrasound,and the difference was statistically significant(P<0.05).The sensitivity and accuracy of high-frequency ultrasound in the diagnosis of cirrhosis and related diseases were 89.29%and 95.41%,which were higher than that of conventional ultrasound(46.43%and 82.57%),and the difference was statistically significant(P<0.05).There was no significant difference in specificity between the two methods(P>0.05).Kappa test showed that there was a good consistency between high-frequency ultrasound and needle biopsy results(Kappa=0.878,P=0.000).The consistency between conventional ultrasound and needle biopsy was fair(Kappa=0.476,P=0.000).Conclusion:High-frequency ultrasound has high application value in the diagnosis of liver cirrhosis and related diseases.It can supplement the deficiency of conventional low-frequency abdominal ultrasound,intuitively analyze the changes of blood flow in the portal vein system of patients with liver cirrhosis,accurately judge t

关 键 词：肝硬化 肝内结节 高频超声 诊断价值 

分 类 号：R445.1[医药卫生—影像医学与核医学]