纳晶微针联合5%米诺地尔酊治疗成人斑秃疗效观察  

Clinical Observation of Nanocrystalline Microneedle Combined with 5%Minoxidil Tincture in the Treatment of Adult Alopecia Areata

作　　者：张艾丽 方杰 王元秋 颜廷凯 黄银浩 王娟 ZHANG Aili;FANG Jie;WANG Yuanqiu;YAN Tingkai;HUANG Yinhao;WANG Juan(Department of Dermatology,the First People's Hospital of Bijie,Bijie 551700,Guizhou,China)

机构地区：[1]毕节市第一人民医院皮肤科,贵州毕节551700

出　　处：《中国美容医学》2023年第8期85-87,共3页Chinese Journal of Aesthetic Medicine

基　　金：毕节市科技计划项目〔编号:毕科联合字SY[2019]5号〕。

摘　　要：目的:评估纳晶微针联合5%米诺地尔酊治疗成人斑秃的疗效及安全性。方法:将入选的68例成人斑秃患者随机分为治疗组36例,对照组32例,对照组单纯外用5%米诺地尔酊治疗,治疗组采用外用5%米诺地尔酊联合纳晶微针促渗导入治疗,对比两组患者的临床疗效及安全性。结果:治疗组有效率为83.33%,对照组有效率71.88%,差异无统计学意义(P>0.05),治疗组治愈率为63.89%,对照组治愈率59.38%,差异无统计学意义(P>0.05)。治疗组的起效时间短于对照组(P<0.05)。结论:纳晶微针联合5%米诺地尔酊治疗成人斑秃安全、有效,较单用5%米诺地尔酊起效快。Objective To evaluate the efficacy and safety of nanocrystalline microneedle combined with 5%minoxidil tincture in the treatment of adult alopecia areata.Methods 68 adult patients with Alopecia areata were randomly divided into treatment group(n=36)and control group(n=32).The control group was treated with 5%minoxidil tincture,and the treatment group was treated with 5%minoxidil tincture combined with nanocrystalline microneedle.The clinical efficacy and safety of the two groups were compared.Results The effective rate and cure rate of the treatment group was 83.33%and 63.89%,respectively,while that of the control group was 71.88%and 59.38%,with no statistical significance(P>0.05).The onset time of the treatment group was shorter than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Nanocrystalline microneedle combined with 5%minoxidil tincture is safe and effective in the treatment of adult alopecia areata,and the effect is faster than that of 5%minoxidil tincture alone.

关 键 词：纳晶微针 5%米诺地尔酊 斑秃 疗效观察 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]