碘营养与甲状腺功能亢进症:共识与争议  

Iodine nutrition and hyperthyroidism:consensus and controversy

作　　者：邢渝敏 单忠艳[1] Xing Yumin;Shan Zhongyan(Department of Endocrinology and Metabolism,Institute of Endocrinology,the First Affiliated Hospital of China Medical University,NHK Key Laboratory of Diagnosis and Treatment of Thyroid Disease,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院内分泌科、国家卫生健康委员会甲状腺疾病重点实验室,沈阳110001

出　　处：《国际内分泌代谢杂志》2023年第4期287-290,共4页International Journal of Endocrinology and Metabolism

摘　　要：碘是合成甲状腺激素的原料,对维持正常的甲状腺功能具有重要作用。甲状腺功能亢进症(甲亢)是内分泌系统常见疾病之一。随着全民食盐加碘政策的实施,碘对甲亢的影响逐渐引起关注。碘摄入量与甲亢的患病呈“U”型曲线,碘摄入量可以影响临床甲亢的患病率,对亚临床甲亢影响不明显。使用含碘药物胺碘酮和含碘造影剂也可导致甲状腺毒症,需要监测易感人群的甲状腺功能。甲亢患者需要摄入适宜的碘,限碘对甲亢无益。碘化钾治疗甲亢的安全性和有效性仍需更多临床试验证实。Iodine is the material for the synthesis of thyroid hormones and plays an important role in maintaining normal thyroid function.Hyperthyroidism is a common disease of endocrine system.With the implementation of the universal salt iodization policy,the effect of iodine on hyperthyroidism has gradually attracted attention.The iodine intake and prevalence of hyperthyroidism show a“U”shaped curve.Iodine nutrition can affect the prevalence of overt hyperthyroidism,but has no obvious effect on subclinical hyperthyroidism.Thyrotoxicosis can also be caused by the use of iodized drugs such as amiodarone and iodized contrast agents,requiring monitoring of thyroid function in susceptible individual.Patients with hyperthyroidism need to take appropriate iodine,and limiting iodine is not beneficial to hyperthyroidism.More clinical trials are needed to confirm the safety and efficacy of potassium iodine in the treatment of hyperthyroidism.

关 键 词：甲状腺功能亢进症 亚临床甲状腺功能亢进 弥漫性毒性甲状腺肿 碘营养 

分 类 号：R581.1[医药卫生—内分泌]