泌尿生殖道支原体感染现状及其耐药性调查  

Current status of urogenital mycoplasma infection and its drug resistance analysis

作　　者：严丽 管湘玉 YAN Li;GUAN Xiang-yu(Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou Jiangsu 215600,China)

机构地区：[1]南京中医药大学附属张家港医院,江苏苏州215600

出　　处：《中国消毒学杂志》2023年第7期519-521,共3页Chinese Journal of Disinfection

基　　金：张家港市中医医院2019年度青年自然科学基金项目(zzyq1913)。

摘　　要：目的研究泌尿生殖道标本中支原体分布及耐药性,为临床感染防控提供参考。方法通过病原学标本分离鉴定和药敏试验方法,对某医院2020年6月—2021年6月患者泌尿道标本支原体及其耐药性进行检测与评价。结果从该医院患者送检的1432份泌尿生殖道标本中检出支原体阳性713份,阳性率49.80%。检出的支原体中,解脲支原体和人型支原体分别占75.32%和3.79%。临床分离的支原体对强力霉素、美满霉素、交沙霉素均比较敏感,对左氧氟沙星、甲砜霉素、司帕沙星和克林霉素等耐药率超过60%。结论该医院患者泌尿生殖道支原体检出率比较高,以解脲支原体为主,对部分抗菌药物出现明显耐药。Objective To investigate the distribution and drug resistance of mycoplasma in genitourinary tract samples,and to provide references for effective clinical prevention and control.Methods Through the isolation and identification of pathogenic specimens and the method of drug susceptibility test,mycoplasma and its drug resistance in the urinary tract specimens of patients in a hospital from June 2020 to June 2021were detected and evaluated.Results 713 of the 1432 urogenital tract samples sent by patients in this hospital were positive for mycoplasma,with a positive rate of 49.80%.Among the mycoplasma detected,Ureaplasma urealyticum and Mycoplasma hominis accounted for 75.32%and 3.79% respectively.Mycoplasma isolated clinically were sensitive to doxycycline,minocycline and josamycin,and the resistance rate to levofloxacin,thiamphenicol,sparfloxacin and clindamycin exceeded 60%.Conclusion TThe detection rate of mycoplasma in the urogenital tract of patients in this hospital is relatively high,mainly Ureaplasma urealyticum,which has obvious resistance to some antibacterial drugs.

关 键 词：泌尿生殖道 支原体 耐药性 

分 类 号：R378[医药卫生—病原生物学]